/*! This file is auto-generated */ .wp-block-button__link{color:#fff;background-color:#32373c;border-radius:9999px;box-shadow:none;text-decoration:none;padding:calc(.667em + 2px) calc(1.333em + 2px);font-size:1.125em}.wp-block-file__button{background:#32373c;color:#fff;text-decoration:none} Q 26. Identify X, an intermediate that... [FREE SOLUTION] | 91影视

91影视

Log out

Learning Materials

Features

Discover

Chapter 26: Q 26. (page 1070)

Identify X, an intermediate that was converted to eletriptan (trade name Relpax), a drug used to treat migraines.

Short Answer

Expert verified

Answer

Step by step solution

01

Heck reaction

The reaction between an alkene and an alkyl halide group in the presence of a base and a catalyst (palladium) is known as the Heck reaction. In this reaction, an alkene is formed.

02

Mechanism of Heck reaction  

  • In the first step, the divalent palladium catalyst reacts with the alkyl halide (RX) to form an organo-palladium compound.
  • In the second step, the (R) group and palladium (Pd) from the organopalladium compound add to the C=C such that Pd bonds with the more substituted carbon.
  • In the third step, the elimination of hydrogen and palladium takes place. Then, by reductive elimination, the initial palladium catalyst is regenerated.
03

Products of the given reaction 

Compound X is shown hereunder.

Compound X

Unlock Step-by-Step Solutions & Ace Your Exams!

  • Full Textbook Solutions

    Get detailed explanations and key concepts

  • Unlimited Al creation

    Al flashcards, explanations, exams and more...

  • Ads-free access

    To over 500 millions flashcards

  • Money-back guarantee

    We refund you if you fail your exam.

Over 30 million students worldwide already upgrade their learning with 91影视!

One App. One Place for Learning.

All the tools & learning materials you need for study success - in one app.

Get started for free

Most popular questions from this chapter

Draw the products formed when each alkene is treated with Grubbs catalyst.

a.

b.

c.

What product is formed by ring-closing metathesis of each compound?

a.

b.

What reagents are needed to convert 2-methylpropene [CH3C=CH2]to each compound? More than one step may be required.

a.

b.

c.

Devise a synthesis of diene A from (Z)-2-bromostyrene as the only organic starting material. Use a Suzuki reaction in one step of the synthesis.

Draw all stereoisomers formed when each alkene is treated with CHCl3and KOC(CH3)3.

a.

b.

c.
See all solutions

Recommended explanations on Chemistry Textbooks

Making Measurements

Read Explanation

Chemical Reactions

Read Explanation

Organic Chemistry

Read Explanation

The Earths Atmosphere

Read Explanation

Chemistry Branches

Read Explanation

Physical Chemistry

Read Explanation
View all explanations

What do you think about this solution?

We value your feedback to improve our textbook solutions.

Study anywhere. Anytime. Across all devices.