91Ó°ÊÓ

Question: Draw the aldol product formed from each compound.

Question: What carbonyl starting materials are needed to prepare each compound using a directed aldol reaction?

Question: What cyclic product is formed when each 1,5-dicarbonyl compound is treated with aqueous $\mathit{O}\mathit{H}$?

Question: What β-keto ester is formed when each ester is used in a Claisen reaction?

Question: Which carbonyl compounds do not undergo an aldol reaction when treated with OH^- in H₂O ?

Question: Two steps in a synthesis of the analgesic ibuprofen, the chapter-opening molecule, include a carbonyl condensation reaction, followed by an alkylation reaction. Identify intermediates A and B in the synthesis of ibuprofen.

Question: What two β-keto esters are formed in the Dieckmann reaction of the following diester?

Question: Which of the following compounds can serve as Michael acceptors?

Question: What product is formed when each pair of compounds is treated with NaOEt in ethanol?

Question: What starting materials are needed to prepare each compound by the Michael reaction?