Chapter 26: Q 19. (page 1068)
What product is formed by ring-closing metathesis of each compound?
a.

b.

Short Answer
Answer
a.

b.

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Chapter 26: Q 19. (page 1068)
What product is formed by ring-closing metathesis of each compound?
a.

b.

Answer
a.

b.

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The following conversion, carried out in the presence of Grubbs catalyst and ethylene gas, involves a cascade of metathesis reactions. Draw a reaction sequence that illustrates how the reactant is converted to the product Z, and indicate where each labeled atom in the reactant ends up in Z.

Although diazomethane ( ) is often not a useful reagent for preparing cyclopropanes,other diazo compounds give good yields of more complex cyclopropanes. Draw a stepwisemechanism for the conversion of diazo compound A to B, an intermediate in the synthesis ofsirenin, the sperm attractant produced by the female gametes of the water mold Allomyces.

Devise a synthesis of each compound using a Heck reaction as one step. You may use benzene, , organic alcohols having two carbons or fewer and any required inorganic reagents.
a.

b.

Identify reagents A and B in the following reaction scheme. This synthetic sequence was used to prepare the C18 juvenile hormone (Figure 20.6).

Draw the products (including stereoisomers) formed in each reaction.


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