Chapter 26: Q19P (page 1049)
What product is formed by ring-closing metathesis of each compound?
a.

b.

Short Answer
a.

b.

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Chapter 26: Q19P (page 1049)
What product is formed by ring-closing metathesis of each compound?
a.

b.

a.

b.

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What starting materials are needed to prepare each compound using a Heck reaction?

Although diazomethane ( ) is often not a useful reagent for preparing cyclopropanes,other diazo compounds give good yields of more complex cyclopropanes. Draw a stepwisemechanism for the conversion of diazo compound A to B, an intermediate in the synthesis ofsirenin, the sperm attractant produced by the female gametes of the water mold Allomyces.

Draw a stepwise mechanism for the following reaction.

Identify X, an intermediate that was converted to eletriptan (trade name Relpax), a drug used to treat migraines.

Draw the product of each coupling reaction.
a.

b.

c.

d.

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