Chapter 5: Q.12 (page 187)
Rank the following groups in order of decreasing priority?
a.
b.
c.
d.
Short Answer
a.
b.
c.
d.
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Chapter 5: Q.12 (page 187)
Rank the following groups in order of decreasing priority?
a.
b.
c.
d.
a.
b.
c.
d.
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A natural product was isolated in the laboratory, and its observed rotation was +10° when measured in a 1 dm sample tube containing 1.0 g of compound in 10 mL of water. What is the specific rotation of this compound?
Draw both enantiomers for each biologically active compound.

amphetamine
(a powerful central nervous stimulant)
a.

ketoprofen
(analgesic and anti-inflammatory agent)
b.
Artemisinin and mefloquine are widely used antimalarial drugs. A ball-and-stick model of artemisinin appears on the cover of this text.
How is compound A related to compounds B–E? Choose from enantiomers, diastereomers, constitutional isomers, or identical molecules.

a) Locate the stereogenic centers in the ball-and-stick model of ezetimibe (trade name Zetia), a cholesterol-lowering drug. (b) Label each stereogenic center as R or S.

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