Chapter 29: Q39. (page 1192)
Draw the organic products formed in each reaction.




Short Answer



c.

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Chapter 29: Q39. (page 1192)
Draw the organic products formed in each reaction.







c.

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Question:Gramicidin S, a topical antibiotic produced by the bacterium Bacillus brevis, is a cyclic decapeptide formed from five amino acids. Draw the structures of the amino acids that form gramicidin S, and explain why this compound possesses two unusual structural features.

Question:Draw the product formed when the following amino acid is treated with each reagent: (a) (b) , pyridine; (c) HCl (1 equiv); (d) NaOH (1 equiv); (e).

As shown in Mechanism 29.2, the final steps in the Edman degradation result in rearrangement of a thiazolinone to an N-phenylthiohydantoin. Draw a stepwise mechanism for this acid-catalyzed reaction.

Write out the steps for the synthesis of each peptide using the Merrifield method:
(a)Ala-Leu-Phe-Phe;
(b) Phe-Gly-Ala-Ile.
Question: Identify the functional groups in each molecule. Classify each alcohol, alkyl halide, amide, and amine as 1°, 2°, or 3°
a.
b.
c. 
d. 
e. 
f. 
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