Chapter 25: 55 (page 1044)
Draw the organic products formed in each reaction.
a

b

c

d

e

f

g

h

i

j

Short Answer
a

b

c

d

e

f

g

h

i

j

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Chapter 25: 55 (page 1044)
Draw the organic products formed in each reaction.
a

b

c

d

e

f

g

h

i

j

a

b

c

d

e

f

g

h

i

j

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Synthesize each compound from benzene. Use a diazonium salt as one of the synthetic intermediates.

Treatment of compound D with followed by forms compound E. D shows a molecular ion in its mass spectrum at m/z= 71 and IR absorptions at and . E shows a molecular ion in its mass spectrum at m/z= 75 and IR absorptions at and . Propose structures for D and E from these data and the given 1H NMR spectra.


Question: Identify the intermediates (A–C) in the following reaction sequence, which was used to prepare racemic ofloxacin. One enantiomer of the product, levofloxacin, is an antibiotic used to treat severe bacterial infections that have not responded to other drugs.

Explain the observed difference in the values of the conjugate acids of amines A and B.

Decide which N atom in each molecule is most basic and draw the product formed when each compound is treated with . Zolpidem (trade name Ambien) is used to treat insomnia, whereas aripiprazole (trade name Abilify) is used to treat depression, schizophrenia, and bipolar disorders.
(a)

(b)

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