Chapter 25: PROBLEM 25.11 (page 1010)
What amine is formed by reduction of each amide?
a.
b.

c.

Short Answer
Answer
a.

b.

c.

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Chapter 25: PROBLEM 25.11 (page 1010)
What amine is formed by reduction of each amide?
a.
b.

c.

Answer
a.

b.

c.

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Devise at least three different methods to prepare N-methylbenzylamine from benzene, any one-carbon organic compounds, and any required reagents.
Question: Safrole, which is isolated from sassafras (Problem 21.33), can be converted to the illegal stimulant MDMA (3,4-methylenedioxymethamphetamine, 鈥淓cstasy鈥) by a variety of methods. (a) Devise a synthesis that begins with safrole and uses a nucleophilic substitution reaction to introduce the amine. (b) Devise a synthesis that begins with safrole and uses reductive amination to introduce the amine.

Question: Draw a structure corresponding to each name.
a. 2,4-dimethylhexan-3-amine
b. N-methylpentan-1-amine
c. N-isopropyl-p-nitroaniline
d. N-methylpiperidine
e. N,N-dimethylethanaminef. 2-aminocyclohexanoneg. N-methylanilineh. m-ethylaniline
Devise a synthesis of each compound from the given starting material(s). Albuterol is a bronchodilator and proparacaine is a local anesthetic.
(a)

(b)

Question: Arrange the compounds in order of increasing boiling point.

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