Chapter 25: 49 (page 1043)
What carbonyl and nitrogen compounds are needed to make each compound by reductive amination? When more than one set of starting materials is possible, give all possible methods.
(a)

(b)

(c)

Short Answer
(a)

(b)

(c)

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Chapter 25: 49 (page 1043)
What carbonyl and nitrogen compounds are needed to make each compound by reductive amination? When more than one set of starting materials is possible, give all possible methods.
(a)

(b)

(c)

(a)

(b)

(c)

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Treatment of compound D with followed by forms compound E. D shows a molecular ion in its mass spectrum at m/z= 71 and IR absorptions at and . E shows a molecular ion in its mass spectrum at m/z= 75 and IR absorptions at and . Propose structures for D and E from these data and the given 1H NMR spectra.


Question: Give a systematic or common name for each compound.
a.

b.

c.

d.

e.

f.

g.

h.

Devise a synthesis of each biologically active compound from benzene.

Question: Draw the product formed when each compound is treated with NaNO2 a²Ô»åâ€Â°ä±ô.
a.

b.

c.

d.

Decide which N atom in each molecule is most basic and draw the product formed when each compound is treated with . Zolpidem (trade name Ambien) is used to treat insomnia, whereas aripiprazole (trade name Abilify) is used to treat depression, schizophrenia, and bipolar disorders.
(a)

(b)

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