/*! This file is auto-generated */ .wp-block-button__link{color:#fff;background-color:#32373c;border-radius:9999px;box-shadow:none;text-decoration:none;padding:calc(.667em + 2px) calc(1.333em + 2px);font-size:1.125em}.wp-block-file__button{background:#32373c;color:#fff;text-decoration:none} Q-21-21-12P Question: How could you prepare ... [FREE SOLUTION] | 91影视

91影视

Log out

Learning Materials

Features

Discover

Chapter 21: Q-21-21-12P (page 699)

Question: How could you prepare the following amides using an acid chloride and an amine or ammonia?

  1. CH3CH2CONHCH3
  1. N,N-Dimethylbenzamide
  1. Propanamide

Short Answer

Expert verified

(a)

CH3CH2COCl+2CH3NH2鈫�CH3CH2CONHCH3N-Methylpropanamide

(b)

(c)

CH3CH2COCl+NH3鈫�CH3CH2CONH2Propanamide

Step by step solution

01

Nuclephilic acyl substitution

The given reactions are examples of nuclephilic acyl substitution reaction.

The leaving grops in teh acyl chlorides is chloride ion. They will be substituted by the nucleophiles.

02

Subpart (a)

The required chemical reaction n is given as:

CH3CH2COCl+2CH3NH2鈫�CH3CH2CONHCH3\hfillN-Methylpropanamide

03

Subpart (b)

The chemical equation for the given reaction is as hown below:

04

Subpart (c)

The nucleophilic acyl substitution for the formation of the given product is as shown below:

CH3CH2COCl+NH3鈫�CH3CH2CONH2Propanamide

Unlock Step-by-Step Solutions & Ace Your Exams!

  • Full Textbook Solutions

    Get detailed explanations and key concepts

  • Unlimited Al creation

    Al flashcards, explanations, exams and more...

  • Ads-free access

    To over 500 millions flashcards

  • Money-back guarantee

    We refund you if you fail your exam.

Over 30 million students worldwide already upgrade their learning with 91影视!

One App. One Place for Learning.

All the tools & learning materials you need for study success - in one app.

Get started for free

Most popular questions from this chapter

What product would you expect from reaction of one equivalent of methanol with a cyclic anhydride, such as phthalic anhydride (1,2-benzenedicarboxylic anhydride)? What is the fate of the second 鈥渉alf鈥� of the anhydride?

Why is the saponification of an ester irreversible? In other words, why doesn鈥檛 treatment of a carboxylic acid with an alkoxide ion yield an ester?

21-75 One frequently used method for preparing methyl esters is by reactionof carboxylic acids with diazomethane, CH2N2

The reaction occurs in two steps: (1) protonation of diazomethane bythe carboxylic acid to yield methyldiazonium ion,, CH3N2+plus a carboxylate ion; and (2) reaction of the carboxylate ion with CH3N2+.
(a) Draw two resonance structures of diazomethane, and account forstep 1.
(b) What kind of reaction occurs in step 2?

Predict the products of the following nucleophilic acyl substitution reactions:

Explain the observation that attempted Fischer esterification of 2,4,6-trimethyl benzoic acid with methanol and HCL is unsuccessful. No ester is obtained, and the acid is recovered unchanged. What alternative method of esterification might be successful?
See all solutions

Recommended explanations on Chemistry Textbooks

Physical Chemistry

Read Explanation

The Earths Atmosphere

Read Explanation

Chemistry Branches

Read Explanation

Kinetics

Read Explanation

Nuclear Chemistry

Read Explanation

Ionic and Molecular Compounds

Read Explanation
View all explanations

What do you think about this solution?

We value your feedback to improve our textbook solutions.

Study anywhere. Anytime. Across all devices.