/*! This file is auto-generated */ .wp-block-button__link{color:#fff;background-color:#32373c;border-radius:9999px;box-shadow:none;text-decoration:none;padding:calc(.667em + 2px) calc(1.333em + 2px);font-size:1.125em}.wp-block-file__button{background:#32373c;color:#fff;text-decoration:none} Q-21-21-12P Question: How could you prepare ... [FREE SOLUTION] | 91影视

91影视

Log out

Learning Materials

Features

Discover

Chapter 21: Q-21-21-12P (page 699)

Question: How could you prepare the following amides using an acid chloride and an amine or ammonia?

  1. CH3CH2CONHCH3
  1. N,N-Dimethylbenzamide
  1. Propanamide

Short Answer

Expert verified

(a)

CH3CH2COCl+2CH3NH2鈫�CH3CH2CONHCH3N-Methylpropanamide

(b)

(c)

CH3CH2COCl+NH3鈫�CH3CH2CONH2Propanamide

Step by step solution

01

Nuclephilic acyl substitution

The given reactions are examples of nuclephilic acyl substitution reaction.

The leaving grops in teh acyl chlorides is chloride ion. They will be substituted by the nucleophiles.

02

Subpart (a)

The required chemical reaction n is given as:

CH3CH2COCl+2CH3NH2鈫�CH3CH2CONHCH3\hfillN-Methylpropanamide

03

Subpart (b)

The chemical equation for the given reaction is as hown below:

04

Subpart (c)

The nucleophilic acyl substitution for the formation of the given product is as shown below:

CH3CH2COCl+NH3鈫�CH3CH2CONH2Propanamide

Unlock Step-by-Step Solutions & Ace Your Exams!

  • Full Textbook Solutions

    Get detailed explanations and key concepts

  • Unlimited Al creation

    Al flashcards, explanations, exams and more...

  • Ads-free access

    To over 500 millions flashcards

  • Money-back guarantee

    We refund you if you fail your exam.

Over 30 million students worldwide already upgrade their learning with 91影视!

One App. One Place for Learning.

All the tools & learning materials you need for study success - in one app.

Get started for free

Most popular questions from this chapter

21-72 Phenyl 4-aminosalicylate is a drug used in the treatment of tuberculosis. Propose a synthesis of this compound starting from 4-nitrosalicylic acid.

21-38 Treatment of an a-amino acid with DCC yields a 2,5-diketopiperazine.Propose a mechanism.

21-36 When 4-dimethylaminopyridine (DMAP) is added in catalytic amountsto acetic anhydride and an alcohol, it significantly increases the rate of ester formation. The process begins with a reaction between acetic anhydride and DMAP to form a highly reactive acetylpyridinium intermediate that is more reactive than acetic anhydride itself. Propose a mechanism for this process that includes the formation and reaction of the acetylpyridinium intermediate.

How would you use the reaction of an amide with LiAlH4 as the key step in going from bromocyclohexane to (N,N-dimethylaminomethyl)cyclohexane? Write all the steps in the reaction sequence.

Predict the products of the following nucleophilic acyl substitution reactions:
See all solutions

Recommended explanations on Chemistry Textbooks

Kinetics

Read Explanation

Chemical Reactions

Read Explanation

Physical Chemistry

Read Explanation

Ionic and Molecular Compounds

Read Explanation

The Earths Atmosphere

Read Explanation

Chemistry Branches

Read Explanation
View all explanations

What do you think about this solution?

We value your feedback to improve our textbook solutions.

Study anywhere. Anytime. Across all devices.