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Clopidogrel can be combined with aspirin to ward off problems related to the heart. It comes in the form of a tablet and can be consumed via the mouth.

Substitution reactions can be of numerous kinds, and one among them is an ${\mathbf{S}}_{\mathbf{N}}\mathbf{2}$ reaction. The nucleophile strikes from the backside in an ${\mathbf{S}}_{\mathbf{N}}\mathbf{2}$ reaction, and an inversion of configuration is observed.

Potassium carbonate functions as the base in this particular reaction. It forms a nucleophile by abstracting the most acidic proton of the reactant.

When the nucleophile reacts with the tosyl group, it strikes on the carbon atom of the C-OTs bond from the backside removing the –OTs group, which is a good nucleophile. This reaction goes via the mechanism. The product of the ${\mathrm{S}}_{\mathrm{N}}2$reaction can be given as:

Synthesis of the antiplatelet agent clopidogrel