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Chapter 29: Q29-2P (page 976)

PROBLEM 29-2Write the equations for the remaining passages of the oxidation pathway following those shown in Figure 29-4.

Short Answer

Expert verified

Theequations for the remaining passages of the oxidation pathwayis given as follows,

CapryloylcoA鈫�Hexanoyl coA鈫�Butyryl coA鈫�2 Acetyl coA

Step by step solution

01

Introduction to the Concept

The 尾-oxidation route catabolizes myristic acid, causing the carbon chain to degrade in stages. The following is the order of events:

02

Solution Explanation

The14-carbon myristoyl COA is converted to the 12-carbon lauroyl COA plus acetyl COA in passage 1, the 10-carbon caproyl COA plus acetyl COA in passage 2, the caproyl COA to the 8-carbon caproyl COA in passage 3, and so on. Because the precursor comprises four carbons, the final passage yields two molecules of acetyl COA.

After six passages, the 尾- oxidationprocess catabolizes the 14-carbon myristic acid, yielding seven molecules of acetyl COA.

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