Chapter 29: Q29-15P (page 1008)
What α-keto acid is formed on transamination of leucine?
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Chapter 29: Q29-15P (page 1008)
What α-keto acid is formed on transamination of leucine?
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Lactate, a product of glucose catabolism in oxygen-starved muscles, can be converted into pyruvate by oxidation. What coenzyme do you think is needed? Write the equation in the normal biochemical format using a curved arrow.

The initial reaction in Problem 29-52, conversion of two molecules of acetyl CoA to one molecule of acetoacetyl CoA, is a Claisen reaction. Assuming that there is a base present, show the mechanism of the reaction.
Draw the structure of adenosine 5’-monophosphate (AMP), an intermediate in some biochemical pathways.
The primary fate of acetyl CoA under normal metabolic conditions is degradation in the citric acid cycle to yield CO2. When the body is stressed by prolonged starvation, however, acetyl CoA is converted into compounds called ketone bodies, which can be used by the brain as a temporary fuel. Fill in the missing information indicated by the four question marks in the following biochemical pathway for the synthesis of ketone bodies from acetyl CoA:

PROBLEM 29-2Write the equations for the remaining passages of the oxidation pathway following those shown in Figure 29-4.
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