Chapter 29: Q29-38E (page 1012)
What general kind of reaction does NAD+ carry out?
Short Answer
NAD+transforms alcohols into aldehydes or ketones, resulting in the formation of NADH and H+ as the side products.
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Chapter 29: Q29-38E (page 1012)
What general kind of reaction does NAD+ carry out?
NAD+transforms alcohols into aldehydes or ketones, resulting in the formation of NADH and H+ as the side products.
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The primary fate of acetyl CoA under normal metabolic conditions is degradation in the citric acid cycle to yield CO2. When the body is stressed by prolonged starvation, however, acetyl CoA is converted into compounds called ketone bodies, which can be used by the brain as a temporary fuel. Fill in the missing information indicated by the four question marks in the following biochemical pathway for the synthesis of ketone bodies from acetyl CoA:

PROBLEM 29-5Evidence for the role of acetate in fatty-acid biosynthesis comes from isotope labelling experiments. If acetate labelled within the methyl group () were incorporated into fatty acids, at what positions in the fatty-acid chain would you expect thelabel to appear?
PROBLEM 29-4Write a mechanism for the dehydration reaction of hydroxybutyryl ACP to yield crotonyl ACP in step 7 of fatty-acid synthesis.
PROBLEM 29-8Look at the entire glycolysis pathway, and make a list of the kinds of organic reactions that take place-nucleophilic acyl substitutions, aldol reactions, E1cB reactions, and so forth.
What enzyme cofactor is associated with each of the following kinds of reactions?
(a) Transamination
(b) Carboxylation of a ketone
(c) Decarboxylation of an
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