Chapter 21: Q52 E (page 726)
21-52 How might you prepare the following compounds from butanoic acid?
- 1-Butanol
- Butanal
- 1-Bromobutane
- Pentanenitrile
- 1-Butene
- 2-Hexanone
Short Answer


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Chapter 21: Q52 E (page 726)
21-52 How might you prepare the following compounds from butanoic acid?


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Explain the observation that attempted Fischer esterification of 2,4,6-trimethyl benzoic acid with methanol and HCL is unsuccessful. No ester is obtained, and the acid is recovered unchanged. What alternative method of esterification might be successful?
Predict the product(s) of the following reactions:

21-50 Answer Problem 21-48 for the reaction of the listed reagents withpropanamide
Name the following compounds:
a.

b.

The following structure represents a tetrahedral alkoxide-ion intermediate formed by addition of a nucleophile to a carboxylic acid derivative. Identify the nucleophile, the leaving group, the starting acid derivative, and the ultimate product (green = Cl).

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