Chapter 29: Q14. (page 1166)
Draw the structure of each peptide. Label the N-terminal and C-terminal amino acids and all amide bonds.
a. Val–Glu
b. Gly–His–Leu
c. M–A–T–T
Short Answer
a.

b.
c.

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Chapter 29: Q14. (page 1166)
Draw the structure of each peptide. Label the N-terminal and C-terminal amino acids and all amide bonds.
a. Val–Glu
b. Gly–His–Leu
c. M–A–T–T
a.

b.
c.

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Draw the structure for each peptide:
(a) Phe–Ala;
(b) Gly–Gln;
(c) Lys–Gly;
(d) R-H
Glutathione, a powerful antioxidant that destroys harmful oxidizing agents in cells, is composed of glutamic acid, cysteine, and glycine, and has the following structure:
Glutathione
a. What product is formed when glutathione reacts with an oxidizing agent?
b. What is unusual about the peptide bond between glutamic acid and cysteine?
Identify the lettered intermediates in the following reaction scheme. This is an alternative method to synthesize amino acids, based on the Gabriel synthesis of 1° amines (Section 25.7A).

Give the amino acid sequence of each peptide using the fragments obtained by partial hydrolysis of the peptide with acid.
(a) What products are formed when each peptide is treated with trypsin? (b) What products are formed when each peptide is treated with chymotrypsin?
[1] Gly–Ala–Phe–Leu–Lys–Ala
[2] Phe–Tyr–Gly–Cys–Arg–Ser
[3] Thr–Pro–Lys–Glu–His–Gly–Phe–Cys–Trp–Val–Val–Phe
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