Chapter 23: Q23-10P (page 764)
What product would you expect to obtain from the base treatment of
Short Answer
It gives seven-member ring fused with the five-member ring.
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Chapter 23: Q23-10P (page 764)
What product would you expect to obtain from the base treatment of
It gives seven-member ring fused with the five-member ring.
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The following reactions are unlikely to provide the indicated product in high yield. What is wrong with each?

Aldol condensation of 3-methyl cyclohexanone leads to a mixture of two enone products, not counting double-bond isomers. Draw them.
Show the products you would expect to obtain by Claisen condensation of the following esters:(a) (CH3)2CHCH2CO2Et (b) Ethyl phenylacetate (c) Ethyl cyclohexyl acetate
In the mixed Claisen reaction of cyclopentanone with ethyl format, a much higher yield of the desired product is obtained by first mixing the two carbonyl components and then adding a base, rather than by first mixing base with cyclopentanone and then adding ethyl format. Explain.
The first step in the citric acid cycle of food metabolism is reaction of oxaloacetate with acetyl CoA to give citrate. Propose a mechanism, using acid or base catalysis as needed.

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