Chapter 23: Q13 P (page 1085)
Which compound is more easily decarboxylated?

Short Answer
Compound 2 is much easier to decarboxylate than compound 1 because of resonance.
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Chapter 23: Q13 P (page 1085)
Which compound is more easily decarboxylated?

Compound 2 is much easier to decarboxylate than compound 1 because of resonance.
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Question: For each of the following reactions, name both the enzyme that catalyzes the reaction and the required coenzyme:
How many conjugated double bonds are there in
a. FAD?
b. FADH2
Explain why the ability of PLP to catalyze an amino acid transformation is greatly reduced if the OH substituent of pyridoxal phosphate is replaced by OCH3.
Explain why the hydrogens of the C-8 methyl group are more acidic than those of the C-7 methyl group.
Acetolactate synthase is another TPP-requiring enzyme. It transfers the acyl group of pyruvate to another molecule of pyruvate, forming acetolactate. This is the first step in the biosynthesis of the amino acids valine and leucine. Propose a mechanism for this reaction.

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