/*! This file is auto-generated */ .wp-block-button__link{color:#fff;background-color:#32373c;border-radius:9999px;box-shadow:none;text-decoration:none;padding:calc(.667em + 2px) calc(1.333em + 2px);font-size:1.125em}.wp-block-file__button{background:#32373c;color:#fff;text-decoration:none} Q21P Question: How do the structures ... [FREE SOLUTION] | 91影视

91影视

Log out

Learning Materials

Features

Discover

Chapter 23: Q21P (page 1092)

Question: How do the structures of tetrahydrofolate and aminopterin differ?

Short Answer

Expert verified

These structures differ by an amino group in tetrahydrofolate and keto group in aminopterin

Step by step solution

01

Tetrahydrofolate and aminopterin drugs

Aminopterin is an anticancer drug, an example of competitive inhibitor. Tetrahydrofolate is the coenzyme derived from reduction of two double bonds from folic acid.The coenzyme is used with enzymes that require transfer of a group containing one carbon to their substrates.

02

Difference in the structure of given drugs

The only difference between two drugs is there is an amino group in 4th position of tetrahydrofolate whereas in aminopterin 4th position is occupied by keto group.


Thus, the structure difference in between tetrahydrofolate and aminopterin is shown above.

Unlock Step-by-Step Solutions & Ace Your Exams!

  • Full Textbook Solutions

    Get detailed explanations and key concepts

  • Unlimited Al creation

    Al flashcards, explanations, exams and more...

  • Ads-free access

    To over 500 millions flashcards

  • Money-back guarantee

    We refund you if you fail your exam.

Over 30 million students worldwide already upgrade their learning with 91影视!

One App. One Place for Learning.

All the tools & learning materials you need for study success - in one app.

Get started for free

Most popular questions from this chapter

Question:Draw the products of the following reaction, where T is tritium:

The enzyme that catalyzes the C伪-C尾bond cleavage reaction that converts serine to glycine removes the substituent (R) bonded to the \(\alpha \)-carbon in the first step of the reaction. Starting with PLP bound to serine in an imine linkage, propose a mechanism for this reaction. (Hint:The first step involves removal of the proton from serine鈥檚 OH group.)

Propose a mechanism for the 伪,尾-elimination reaction shown on page 1082.

Question: Propose a mechanism for the following reaction:

Which compound is more easily decarboxylated?
See all solutions

Recommended explanations on Chemistry Textbooks

The Earths Atmosphere

Read Explanation

Nuclear Chemistry

Read Explanation

Organic Chemistry

Read Explanation

Chemistry Branches

Read Explanation

Kinetics

Read Explanation

Ionic and Molecular Compounds

Read Explanation
View all explanations

What do you think about this solution?

We value your feedback to improve our textbook solutions.

Study anywhere. Anytime. Across all devices.