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F.C. Crick suggested the theory in the year 1996. According to this theory, wobble base pair is the hydrogen-bonded base pairing that occurs between the nucleotides in the molecule of RNA and it does not follow the regulations of Watson-Crick base pair theory.

Wobble base pairs are more common in transfer ribonucleic acids (tRNAs), and they play a key role in codon-anticodon interactions. In the four wobble base pairs, hypoxanthine-adenine is one of the most important.

It demonstrates that the oxygen (O) atom of hypoxanthinehas coupled with one of the hydrogen (H) groups in the ammonia (NH鈧�) group ofcytosineand this is linked to hypoxanthine nitrogen (N) bound with N in cytosine.

Thus, in a base pair structure, hypoxanthine is linked to nitrogen in the cytosine.