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Chapter 3: Q3. (page 77)

In many organisms, DNA is modified by methylation. Draw the structure of 5-methylcytosine, a base that occurs with high frequency in inactive DNA.

Short Answer

Expert verified

The structure of 5-methylcytosine is:

Step by step solution

01

Introduction

A DNA molecule is made up of helical strands comprising of nucleotide base pairs that carry genetic instructions for the growth, development, function, and reproduction all living species.

The addition of methyl groups to nucleotides in a DNA molecule changes the structure of the DNA molecule. The nucleotide sequences of DNA do not change after methylation, however the expression of methylated genes may alter.

02

5-Methylcytosine

When the methyl group is added to the 5th carbon atom of cytosine without changing its base-pairing characteristics, 5-methylcytosine is generated.5-Methylcytosine has a role in gene transcription control.

03

Pictorial representation of methylation of cytosine

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Most popular questions from this chapter

Name the following nucleotide.

Using the data in Table 3-2, identify restriction enzymes that (a) produce blunt ends; (b) recognize and cleave the same sequence (called isoschizomers); (c) produce identical sticky ends.

Question: Identify the purines and pyrimidines commonly found in nucleic acids.

Question: What are some of the challenges of expressing a eukaryotic gene in a prokaryotic host cell?

The human genome contains thousands of sequences known as small open reading frames, some of which encode proteins of about 30 amino acids. What is the minimum number of nucleotides required to encode such a protein?
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