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Chapter 3: Q29. (page 78)

The adenine derivative hypoxanthine can base-pair with adenine. Draw the structure of this base pair.

Short Answer

Expert verified

The base pair structure of hypoxanthine with adenine is,

Step by step solution

01

Introduction

Wobble base pair refers to anH-bonded base pairing between two nucleotides in an RNA molecule that does not follow Watson-Crick base pair regulations. In 1996, F.C. Crick suggested the theory.

Wobble base pairs are more common in transfer ribonucleic acids (tRNAs), and they play a key role in codon-anticodon interactions. In the four wobble base pairs, hypoxanthine-adenine is one of the most important.

02

Pictorial representation of Base pair structure of hypoxanthine with adenine

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Most popular questions from this chapter

The pK value for N1 of adenine is 3.64, whereas the pK value for N1 of guanine is 9.50. Explain this difference.

Hypoxanthine can also base-pair with cytosine. Draw the structure of this base pair.

Using a three-dimensional computer model of the DNA molecule (such as shown in Interactive Exercise 1), identify each of the following structural features: the 3鈥� and 5鈥� end of each strand, the atoms that make up the sugar-phosphate backbone, the major and minor grooves, the bases in several base pairs, and the atoms that participate in hydrogen bonding in A =T and G=C base pairs.

An enzyme from the human immunodeficiency virus (HIV, which causes AIDS) can synthesize DNA from an RNA template. Explain how this enzyme activity contradicts Crick鈥檚 central dogma.

The human genome contains thousands of sequences known as small open reading frames, some of which encode proteins of about 30 amino acids. What is the minimum number of nucleotides required to encode such a protein?
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