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Side effects A drug manufacturer claims that less than 10%of patients who take its new drug for treating Alzheimer鈥檚 disease will experience nausea. To test this claim, researchers conduct an experiment. They give the new drug to a random sample of 300out of 5000Alzheimer鈥檚 patients whose families have given informed consent for the patients to participate in the study. In all, 25of the subjects experience nausea.

a. Describe a Type I error and a Type II error in this setting, and give a possible

consequence of each.

b. Do these data provide convincing evidence for the drug manufacturer鈥檚 claim?

Short Answer

Expert verified

a. Type I error: Doctors underestimate patients experiencing nausea.

Type II error: Doctors overestimate patients experiencing nausea.

b. No convincing evidence is present for manufacturer's claim is false.

Step by step solution

01

Given Information

It is given that =0.05

n=300

x=25

Claim is less than10%

02

Type I and type II error

According to given data:

Null hypothesis: H0:p=10%=0.10

Alternate hypothesis: H1:p<0.10

Type I error: There is proof that percentage of patients suffering from nausea <10%where the percentage of patients experience nausea is actually 10%

Consequence can be that doctors underestimate patients experiencing nausea are side effects are worse.

Type II error: There is sufficient convincing proof that percentage of patients suffering from nausea <10%where the percentage of patients experience nausea is actually 10%

Consequence is doctors overestimate patients experiencing nausea and side effects are better than expected.

03

If given data prove the manufacturer's claim.

The condition of normality is: np0=300(0.10)=30and n1-p0=300(1-0.10)=300(0.90)=270

Both are greater than 10

We can use hypothesis test.

Sample proportion: p^=xn=25300=112=0.0833

Test static: z=p^-p0p01-p0n=0.0833-0.100.10(1-0.10)300=-0.96

Pvalue is P=P(Z<-0.96)=0.1685

Now, P>0.05Fail to rejectH0

There is not convincing evidence that manufacturer's claim is false.

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