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The article "Measuring the Exposure of Infants to Tobacco Smoke" (New England J. of Medicine, 1984: 1075-1078) reports on a study in which various measurements were taken both from a random sample of infants who had been exposed to household smoke and from a sample of unexposed infants. The accompanying data consists of observations on urinary concentration of cotanine, a major metabolite of nicotine (the values constitute a subset of the original data and were read from a plot that appeared in the article). Does the data suggest that true average cotanine level is higher in exposed infants than in unexposed infants by more than 25 ? Carry out a test at significance level .05.

Short Answer

Expert verified

Therefore,

Reject null hypothesis.

Step by step solution

01

Given.

Given:

When testing null hypothesis

\({H_0}:{\mu _1} - {\mu _2} = {\Delta _0}\)

versus one of the alternative hypothesis, one could use test statistic value

\(w = \sum\limits_{i = 1}^m {{r_i}} \)

where\({r_i}\)is rank of\(\left( {{x_i} - {\Delta _0}} \right)\) in the combined sample of\(m + n{\left( {x - {\Delta _0}} \right)^\prime }\)s and\({y^\prime }\)s.

The\(P\)-value depends on alternative hypothesis
Alternative\({{\rm{H}}_y}\)pothesis\({P_{{\rm{ - value }}}}\)

\(\begin{array}{*{20}{l}}{{H_a}:{\mu _1} - {\mu _2} > {\Delta _0}}&{{P_0}(W \ge w)}\\{{I_a}:{\mu _1} - {\mu _2} < {\Delta _0}}&{{P_0}(W \le w) = {P_0}(W \ge m(mn + n + 1) - w)}\\{{I_a}:{\mu _1} - {\mu _2} \ne {\Delta _0}}&{2{P_0}(W \ge \max \{ w,m(m + n + 1) - w)}\end{array}\)

Use Table\(A.14\)to determine\(P\)-values (use closest value to corresponding significance level to make conclusions).
The null hypotheses of interest are

\({H_0}:{\mu _1} - {\mu _2} = - 25\)

versus alternative hypothesis

\({H_a}:{\mu _1} - {\mu _2} < - 25,\)

The following table represents required data to compute test statistic value.

02

To determine the rank of every data value.

\(i\)

\({x_i}/{y_i}\)

\({x_i} - ( - 25)/{y_i}\)

\({r_i}\)

\(\sum {{r_i}} \)

\(1\)

\(8\)

\(33\)

\(1\)

\(2\)

\(11\)

\(36\)

\(3\)

\(3\)

\(12\)

\(37\)

\(4\)

\(4\)

\(14\)

\(39\)

\(5\)

\(5\)

\(20\)

\(45\)

\(6\)

\(6\)

\(13\)

\(68\)

\(8\)

\(m = 7\)

\(111\)

\(136\)

\(12\)

\(39\)

\(1\)

\(35\)

\(35\)

\(2\)

\(2\)

\(56\)

\(56\)

\(7\)

\(3\)

\(83\)

\(83\)

\(9\)

\(4\)

\(92\)

\(92\)

\(10\)

\(5\)

\(128\)

\(128\)

\(11\)

\(6\)

\(150\)

\(150\)

\(13\)

\(7\)

\(176\)

\(176\)

\(14\)

\(n = 8\)

\(208\)

\(208\)

\(15\)

\(81\)

03

To find P value.

The alternative hypothesis is lower-sided; thus, the\(P\)-value is

\({P_0}(W \le w) = {P_0}(W \ge m(m + n + 1) - w) = {P_0}(W \ge 73)\)

Using the table in appendix, for

\(\begin{array}{l}\alpha = 0.05,\\m = 7,\\n = 8,\end{array}\)

\(P\)value is

\({P_0}(W \ge 73) = 0.027,\)

the corresponding\(P\)-value is less than\(0.05\).

Hence,reject null hypothesisat given significance level, the true average level for exposed infants appears to exceed the unexposed infants by more than
25.

Do not reject null hypothesis at significance level \({\rm{0}}{\rm{.01}}\) .

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Most popular questions from this chapter

A random sample of 15 automobile mechanics certified to work on a certain type of car was selected, and the time (in minutes) necessary for each one to diagnose a particular problem was determined, resulting in the following data:

30.6 30.1 15.6 26.7 27.1 25.4 35.0 30.8

31.6 53.2 12.5 23.2 8.8 24.9 30.2

Use the Wilcoxon test at significance level .10 to decide whether the data suggests that true average diagnostic time is less than 30 minutes.

The article "'Multimodal Versus Unimodal Instruction in a Complex Learning Environment" (J. of Experimental Educ., 2002: 215鈥239) described an experiment carried out to compare students' mastery of certain software learned in two different ways. The first learning method (multimodal instruction) involved the use of a visual manual. The second technique (unimodal instruction) employed a textual manual. Here are exam scores for the two groups at the end of the experiment (assignment to the groups was random):

Does the data suggest that the true average score depends on which learning method is used?

Suppose we wish to test.

: the X and Y distributions are identical

versus

: the X distribution is less spread out than the Y

distribution

The accompanying figure pictures X and Y distributions for which is true. The Wilcoxon rank-sum test is not appropriate in this situation because when is true as pictured, the Y鈥檚 will tend to be at the extreme ends of the combined sample (resulting in small and large Y ranks), so the sum of X ranks will result in a W value that is neither large nor small.

Consider modifying the procedure for assigning ranks as follows: After the combined sample of m + n observations is ordered, the smallest observation is given rank 1, the largest observation is given rank 2, the second smallest is

given rank 3, the second largest is given rank 4, and so on. Then if is true as pictured, the X values will tend to be in the middle of the sample and thus receive large ranks. Let W鈥 denote the sum of the X ranks and consider an uppertailed test based on this test statistic. When is true, every possible set of X ranks has the same probability, so W鈥 has the same distribution as does W when H0 is true. The accompanying data refers to medial muscle thickness for arterioles from the lungs of children who died from sudden infant death syndrome (x鈥檚) and a control group of children (y鈥檚). Carry out the test of versus at level .05.

SIDS 4.0 4.4 4.8 4.9

Control 3.7 4.1 4.3 5.1 5.6

Consult the Lehmann book (in the chapter bibliography) for more information on this test, called the Siegel-Tukey test.

Say as much as you can about the P-value for the rank sum test in each of the following situations.

a. m = 5, n 5 6, w 5 41, upper-tailed test.

b. m = 5, n 5 6, w 5 22, lower-tailed test.

c. m = 5, n 5 6, w 5 45, two-tailed test.

d. m = n 5 12, upper-tailed test, x ranks 5 4, 7, 8, 11, 12, 15, 17, 19, 20, 22, 23, 24.

The accompanying data on cortisol level was reported in the article 鈥淐ortisol, Cortisone, and 11-Deoxycortisol Levels in Human Umbilical and Maternal Plasma in Relation to the Onset of Labor鈥 (J. of Obstetric Gynaecology of the British Commonwealth, 1974: 737鈥745). Experimental subjects were pregnant women whose babies were delivered between 38 and 42 weeks gestation. Group 1 individuals elected to deliver by Caesarean section before labor onset, group 2 delivered by emergency Caesarean during induced labor, and group 3 individuals experienced spontaneous labor. Use the Kruskal-Wallis test at level .05 to test for equality of the three population means.

Group 1 262 307 211 323 452 339

304 154 287 356

Group 2 467 501 455 355 468 362

Group 3 343 772 207 1048 838 687

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