/*! This file is auto-generated */ .wp-block-button__link{color:#fff;background-color:#32373c;border-radius:9999px;box-shadow:none;text-decoration:none;padding:calc(.667em + 2px) calc(1.333em + 2px);font-size:1.125em}.wp-block-file__button{background:#32373c;color:#fff;text-decoration:none} Problem 2 What important products of the c... [FREE SOLUTION] | 91影视

91影视

Log out

Learning Materials

Features

Discover

Chapter 12: Problem 2

What important products of the citric acid cycle are required for gluconeogenesis from pyruvate?

Short Answer

Expert verified
The important products of the citric acid cycle required for gluconeogenesis from pyruvate include NADH and GTP.

Step by step solution

01

Identify Products of Citric Acid Cycle

The key products of the citric acid cycle include 3 NADH, 1 FADH2, 2 CO2, 1 GTP and 2 H+. Here the most relevant for our problem are NADH and GTP.
02

Understand Gluconeogenesis

Gluconeogenesis is the metabolic process by which organisms produce glucose. It is a complex process which involves the conversion of pyruvate into glucose. The main precursors for gluconeogenesis are lactate, all citric acid cycle intermediates (through conversion to oxaloacetate), certain amino acids, and glycerol.
03

Identify Required Products for Gluconeogenesis

In this conversion, reducing potential in the form of NADH and GTP (a form of energy) are needed. NADH is used for the conversion of 1,3-bisphosphoglycerate to glyceraldehyde 3-phosphate, GTP is used for the conversion of oxaloacetate to phosphoenolpyruvate.
04

Make The Connection

According to the requirements of gluconeogenesis, products of the citric acid cycle that are obligatory for this process include NADH and GTP. Both are produced in the Krebs cycle and used in the gluconeogenesis pathway to synthesize glucose.

Unlock Step-by-Step Solutions & Ace Your Exams!

  • Full Textbook Solutions

    Get detailed explanations and key concepts

  • Unlimited Al creation

    Al flashcards, explanations, exams and more...

  • Ads-free access

    To over 500 millions flashcards

  • Money-back guarantee

    We refund you if you fail your exam.

Over 30 million students worldwide already upgrade their learning with 91影视!

One App. One Place for Learning.

All the tools & learning materials you need for study success - in one app.

Get started for free

Most popular questions from this chapter

Glycogen storage diseases (GSDs) due to specific enzyme deficiencies can affect the balance between glycogen stores and blood glucose. Given the following diseases, predict the effects of each on (1) the amount of liver glycogen stored and (2) blood glucose levels. (a) Von Gierke disease (GSD-1a), defective enzyme: glucose 6-phosphatase. (b) Cori's disease (GSD III), defective enzyme: amylo1,6 glucosidase (debranching enzyme). (c) Hers's disease (GSD VI), defective enzyme: liver phosphorylase

(a) Draw the structures of the reactants and products for the second reaction catalyzed by transketolase in the pentose phosphate pathway. Show which carbons are transferred. (b) When \(2-\left[{ }^{14} \mathrm{C}\right]\)-glucose 6-phosphate enters the pathway, which atom of fructose 6-phosphate produced by the reaction in Part (a) is labeled? (c) When \(2-\left[{ }^{14} \mathrm{C}\right]\)-glucose 6-phosphate enters the pathway, which atom of fructose 6-phosphate produced by the transaldolase reaction is labeled?

After glycogen reserves are depleted what are the major gluconeogenic precursors of glucose under the conditions of (a) starvation and (b) intense exercise?

When the concentration of glucagon rises in the blood, which of the following enzyme activities is decreased? Explain. Adenylyl cyclase Protein kinase A PFK-2 (kinase activity) Fructose 1, 6-bisphosphatase

The pentose phosphate pathway and the glycolytic pathway are interdependent, since they have in common several metabolites whose concentrations affect the rates of enzymes in both pathways. Which metabolites are common to both pathways?
See all solutions

Recommended explanations on Chemistry Textbooks

Inorganic Chemistry

Read Explanation

Making Measurements

Read Explanation

Ionic and Molecular Compounds

Read Explanation

The Earths Atmosphere

Read Explanation

Chemistry Branches

Read Explanation

Nuclear Chemistry

Read Explanation
View all explanations

What do you think about this solution?

We value your feedback to improve our textbook solutions.

Study anywhere. Anytime. Across all devices.