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Chapter 24: Q46P (page 1126)

What are four possible fates of pyruvate in a mammalian cell?

Short Answer

Expert verified

The answer is,

Alanine Lactate Acetyl-CoA Oxaloacetate

Step by step solution

01

Pyruvate ion

The Pyruvate ion is an anion containing three carbon, three oxygen and three hydrogen atoms. The structure of pyruvate is as shown below.

Pyruvate

02

Explanation

The pyruvate can be converted to alanine (transamination), oxaloacetate (carboxylation), lactate (reduction) and acetyl- CoA (by the pyruvate dehydrogenase complex).

Alanine Lactate Acetyl-CoA Oxaloacetate

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Most popular questions from this chapter

Explain why the conversion of pyruvate to lactate is a reversible reaction, but the conversion of pyruvate to acetaldehyde is not reversible.

Oxidation of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate is an endergonic reaction, but the flow through this point in glycolysis proceeds smoothly. How is the unfavorable equilibrium constant overcome?

Do the calculation showing that at pH 7.4

a.the charge on ADP is -2.8. b. the charge on the alkyl phosphate is -1.8.

Which carbon atoms of glucose end up as a carboxyl group in pyruvate?

UDP- galactose- 4- epimerase converts UDP- galactose to UDP- glucose. The reaction requires NAD+ as a coenzyme.

a. Propose a mechanism for the reaction.

b. Why is the enzyme called an epimerase?

UDP-galactose UDP- glucose
See all solutions

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