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Chapter 21: Q34P (page 1010)

Show the steps in the synthesis of the tetrapeptide Leu- Phe- Ala- Val

Short Answer

Expert verified

The answer is:

Step 1

Step 2

Step 3

Step by step solution

01

Step-by-Step Solution Step 1: Cysteine

There are a large number of amino acids in nature. Out of these, some are essential, and some are non-essential amino acids. Cysteine is an amino acid containing a sulfur atom.

02

Explanation

The steps in the synthesis of the tetrapeptide Leu- Phe- Ala- Val

Step 1


Step 2

Step 3

The obtained compound reacts with the trifluoroacetic acid and dichloromethane to give the final tetrapeptide.

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Most popular questions from this chapter

Draw the tetrapeptide Ala-Thr-Asp-Asn and indicate the peptide bonds.

a. Calculate the overall yield of bradykinin when the yield for the addition of each amino acid to the chain is 70%.

b. What would be the overall yield of a peptide containing 15 amino acids if the yield for the incorporation of each is 80%?

In what order would histidine, serine, aspartate, and valine be eluted with a buffer of pH 4 from a columncontaining an anion-exchange resin (Dowex 1)?

Draw the predominant form for glutamate in a solution with the following pH:

a.0 b. 3 c. 6 d. 11

Write the mechanism for the reaction of a cysteine side chain with iodoacetic acid.
See all solutions

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