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Chapter 21: Q34P (page 1010)

Show the steps in the synthesis of the tetrapeptide Leu- Phe- Ala- Val

Short Answer

Expert verified

The answer is:

Step 1

Step 2

Step 3

Step by step solution

01

Step-by-Step Solution Step 1: Cysteine

There are a large number of amino acids in nature. Out of these, some are essential, and some are non-essential amino acids. Cysteine is an amino acid containing a sulfur atom.

02

Explanation

The steps in the synthesis of the tetrapeptide Leu- Phe- Ala- Val

Step 1


Step 2

Step 3

The obtained compound reacts with the trifluoroacetic acid and dichloromethane to give the final tetrapeptide.

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Most popular questions from this chapter

Draw the form of aspartate that predominates at the following pH values:

a. pH = 1.0 b. pH = 2.6 c. pH = 6.0 d. pH = 11.0

What amino acid is formed when the aldehyde used in the Strecker synthesis is

a. acetaldehyde? b. 2-methylbutanal? c. 3-methylbutanal?

Calculate the pI of each of the following amino acids:

a.asparagine b. arginine c. serine d. aspartate

An opioid pentapeptide has the following structure: Tyr-Cys-Gly-Phe-Cys

a. Draw the structure of the pentapeptide including all the side chains.

b. Write its structure following mild oxidation.

A mixture of amino acids that do not separate sufficiently when a single technique is used can often be separated by two-dimensional chromatography.In this technique, the mixture of amino acids is applied to a piece of filter paper and separated by chromatographic techniques. The paper is then rotated90掳,and the amino acids are further separated by electrophoresis, producing a type of chromatogram called a fingerprint.Identify the spots in the fingerprint obtainedfrom a mixture of Ser, Glu, Leu, His, Met, and Thr.
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