Chapter 21: Q15P (page 997)
What aldehyde is formed when valine is treated with ninhydrin?
Short Answer
The aldehyde formed is 2-methyl propanal.
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Chapter 21: Q15P (page 997)
What aldehyde is formed when valine is treated with ninhydrin?
The aldehyde formed is 2-methyl propanal.
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a.Which amino acid has the lowest pI value?
b.Which amino acid has the highest pI value?
c.Which amino acid has the greatest amount of negative charge at pH = 6.20?
d.Which amino acid has a greater negative charge at pH = 6.20, glycine or methionine?
alpha- Amino acids can be prepared by treating an aldehyde with ammonia/trace acid, followed by hydrogen cyanide, followed by acid-catalyzed hydrolysis.
a. Draw the structures of the two intermediates formed in this reaction.
b. What amino acid is formed when the aldehyde that is used is 3-methylbutanal?
c. What aldehyde is needed to prepare isoleucine?
Reaction of a polypeptide with carboxypeptidase A releases Met. The polypeptide undergoes partial hydrolysis to give the following peptides.
What is the sequence of the polypeptide?
1. Ser, Lys, Trp4. Leu, Glu, Ser 7. Glu, His 10. Glu, His, Val
2. Gly, His, Ala 5. Met, Ala, Gly8. Leu, Lys, Trp11. Trp, Leu, Glu
3. Glu, Val, Ser 6. Ser, Lys, Val 9. Lys, Ser 12. Ala, Met
Draw the predominant form for glutamate in a solution with the following pH:
a.0 b. 3 c. 6 d. 11
Show the steps in the synthesis of the tetrapeptide Leu- Phe- Ala- Val
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