Chapter 15: Problem 22
Histones are thought to be displaced as RNA polymerase is transcribing a gene. What would be the potentially harmful consequences if histones were not put back onto a gene after RNA polymerase had passed?
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Chapter 15: Problem 22
Histones are thought to be displaced as RNA polymerase is transcribing a gene. What would be the potentially harmful consequences if histones were not put back onto a gene after RNA polymerase had passed?
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Briefly describe three ways that ATP-dependent chromatin-remodeling complexes may change chromatin structure.
Transcription factors usually contain one or more motifs that play key roles in their function. What is the function of the following motifs? A. Helix-turn-helix B. Zinc finger C. Leucine zipper
Explain how the acetylation of core histones may loosen chromatin packing.
Discuss the common points of control in eukaryotic gene regulation.
An enhancer, located upstream from a gene, has the following sequence: $$ \begin{aligned} &5^{\prime}-\mathrm{GTAG}-3^{\prime} \\ &3^{\prime}-\mathrm{CATC}-5^{\prime} \end{aligned} $$ This enhancer is orientation-independent. Which of the following sequences also works as an enhancer? A. 5'-CTAC-3' \(3^{\prime}-\mathrm{GATG}-5^{\prime}\) B. \(5^{\prime}-\mathrm{GATG}-3^{\prime}\) \(3^{\prime}-\mathrm{CTAC}-5^{\prime}\) C. \(5^{\prime}-\mathrm{CATC}-3^{\prime}\) \(3^{\prime}-\mathrm{GTAG}-5^{\prime}\)
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