/*! This file is auto-generated */ .wp-block-button__link{color:#fff;background-color:#32373c;border-radius:9999px;box-shadow:none;text-decoration:none;padding:calc(.667em + 2px) calc(1.333em + 2px);font-size:1.125em}.wp-block-file__button{background:#32373c;color:#fff;text-decoration:none} Q17P Is allopurinol a mechanism-based... [FREE SOLUTION] | 91影视

91影视

Log out

Learning Materials

Features

Discover

Chapter 23: Q17P (page 829)

Is allopurinol a mechanism-based inhibitor of xanthine oxidase?

Short Answer

Expert verified

Allopurinol is a mechanism-based inhibitor of xanthine oxidase because its oxidation product irreversibly inhibits the enzyme.

Step by step solution

01

Definition of Concept

Alloxanthine is produced when allopurinol is oxidized by xanthine oxidase.

02

Step 2:Explain the allopurinol is a mechanism-based inhibitor of xanthine oxidase or not

Alloxanthine binds irreversibly to a reduced form of xanthine oxidase, inactivating the enzyme.

A mechanism-based inhibitor is a molecule that goes through enzyme activity and produces an irreversible inhibitor of the enzyme.

Therefore, the allopurinol is a mechanism-based inhibitor of xanthine oxidase because its oxidation product irreversibly inhibits the enzyme.

Unlock Step-by-Step Solutions & Ace Your Exams!

  • Full Textbook Solutions

    Get detailed explanations and key concepts

  • Unlimited Al creation

    Al flashcards, explanations, exams and more...

  • Ads-free access

    To over 500 millions flashcards

  • Money-back guarantee

    We refund you if you fail your exam.

Over 30 million students worldwide already upgrade their learning with 91影视!

One App. One Place for Learning.

All the tools & learning materials you need for study success - in one app.

Get started for free

Most popular questions from this chapter

Rats are given cytidine that is14C-labeled at both its base and ribose components. Their DNA is then extracted and degraded with nucleases. Describe the labeling pattern of the recovered deoxycytidylate residues if deoxycytidylate production in the cell followed a pathway in which (a) intact CDP is reduced to dCDP, and (b) CDP is broken down to cytosine and ribose before reduction.

What is the role of NADPH in the formation of thymidylate?

Compare the pathways of purine and pyrimidine nucleotide synthesis with respect to (a) precursors, (b) energy cost, (c) acquisition of the ribose moiety, and (d) number of enzymatic steps.

How does 2-azahypoxanthine, a fungal product that stimulates plant growth, differ from guanine?

Why is gout more prevalent in populations that eat relatively large amounts of meat?
See all solutions

Recommended explanations on Biology Textbooks

Control of Gene Expression

Read Explanation

Cells

Read Explanation

Bioenergetics

Read Explanation

Chemistry of Life

Read Explanation

Biology Experiments

Read Explanation

Biological Processes

Read Explanation
View all explanations

What do you think about this solution?

We value your feedback to improve our textbook solutions.

Study anywhere. Anytime. Across all devices.