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Fructose enters the glycolytic pathway through fructose-1-phosphate. In the liver, isomerization of fructose-1-phosphate to fructose-6-phosphate, a glycolysis intermediate, occurs.

Mannose becomes mannose-6-phosphate when it is phosphorylated. The enzyme phosphomannose isomerase converts mannose-6-phosphate to fructose-6-phosphate, which subsequently enters the glycolytic route or the gluconeogenic pathway of hepatocytes, where it is transformed to glucose-6-phosphate.

The enzymatic process converts galactose to glucose-6-phosphate, a glycolytic intermediate that enters the glycolytic pathway.

Hence,mannose is phosphorylated to mannose-6-phosphate by fructose entering the glycolytic pathway. The enzymatic mechanism transforms galactose into glucose-6-phosphate.