Chapter 9: Q. 23 (page 252)
What is the difference between intracellular signaling and intercellular signaling?
Short Answer
Intracellular signaling is communication within a cell and intercellular signaling is communication between the cells.
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Chapter 9: Q. 23 (page 252)
What is the difference between intracellular signaling and intercellular signaling?
Intracellular signaling is communication within a cell and intercellular signaling is communication between the cells.
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A scientist notices that a cancer cell line shows high levels of phosphorylated ERK in the absence of EGF. What are two possible explanations for the increase in phosphorylated ERK? Be specific in which proteins are involved.
A scientist observes a mutation in the transmembrane region of EGFR that eliminates its ability to be stabilized by binding interactions during dimerization after ligand binding. Which hypothesis regarding the effect of this mutation on EGF signaling is most likely to be correct?
a. EGF signaling cascades would be active for longer in the cell.
b. EGF signaling cascades would be active for a shorter period of time in the cell.
c. EGF signaling cascades would not occur.
d. EGF signaling would be unaffected.
What is the function of a phosphatase?
a. A phosphatase removes phosphorylated amino acids from proteins.
b. A phosphatase removes the phosphate group from phosphorylated amino acid residues in a protein.
c. A phosphatase phosphorylates serine, threonine, and tyrosine residues.
d. A phosphatase degrades second messengers in the cell.
Cells grown in the laboratory are mixed with a dye molecule that is unable to pass through the plasma membrane. If a ligand is added to the cells, observations show that the dye enters the cells. What type of receptor did the ligand bind to on the cell surface?
What property enables the residues of the amino acids serine, threonine, and tyrosine to be phosphorylated?
a. They are polar.
b. They are non-polar.
c. They contain a hydroxyl group.
d. They occur more frequently in the amino acid sequence of signaling proteins.
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