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Chapter 9: Q. 23 (page 252)
What is the difference between intracellular signaling and intercellular signaling?
Intracellular signaling is communication within a cell and intercellular signaling is communication between the cells.
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A scientist notices that a cancer cell line shows high levels of phosphorylated ERK in the absence of EGF. What are two possible explanations for the increase in phosphorylated ERK? Be specific in which proteins are involved.
Histamine binds to the H1 G-protein-linked receptor to initiate the itchiness and airway constriction associated with an allergic response. If a mutation in the associated G-protein鈥檚 alpha subunit prevented the hydrolysis of GTP how would the allergic response change? a. More severe allergic response compared to normal G-protein signaling. b. Less severe allergic response compared to normal G-protein signaling. c. No allergic response. d. No change compared to normal G-protein signaling.
Which of the following statements about quorum sensing is false?
a. Autoinducer must bind to receptor to turn on transcription of genes responsible for the production of more autoinducer.
b. The receptor stays in the bacterial cell, but the autoinducer diffuses out.
c. Autoinducer can only act on a different cell: it cannot act on the cell in which it is made.
d. Autoinducer turns on genes that enable the bacteria to form a biofilm.
Which type of molecule acts as a signaling molecule in yeasts?
a. steroid
b. autoinducer
c. mating factor
d. second messenger
What are the differences between internal receptors and cell-surface receptors?
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