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Chapter 5: Q 62. (page 312)

Treating low bone density (4.2) Fractures of the spine are common and serious among women with advanced osteoporosis (low mineral density in the

bones). Can taking strontium ranelate help? A large medical trial assigned 1649 women to take either strontium ranelate or a placebo each day. All of

the subjects had osteoporosis and had had at least one fracture. All were taking calcium supplements and receiving standard medical care. The response variables were measurements of bone density and counts of new fractures over three years. The subjects were treated at 10 medical centers in 10 different countries.9 Outline an appropriate design for this experiment. Explain why this is the proper design.

Short Answer

Expert verified

The design that has been outlined is appropriate.

Step by step solution

01

Step 1. Given Information

1649 women with at least one fracture were recruited for the study. These women will be treated at ten medical centers in ten different nations.

02

Step 2. Concept Used

Definition of the probability addition theorem: Assume A and B are two events in a random experiment, and you want to know whether A or B has a higher likelihood. Then apply the probability addition theorem.

03

Step 3. Explanation

The experiment is outlined as:

Because subjects were chosen at random for treatment and a placebo group was included in the experiment, the specified design is said to be suitable.

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