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Scientists and engineers frequently wish to compare two different techniques for measuring or determining the value of a variable. In such situations, interest centers on testing whether the mean difference in measurements is zero. The article "Evaluation of the Deuterium Dilution Technique Against the Test Weighing Procedure for the Determination of Breast Milk Intake" (Amer: J. of Clinical Nutr., \(1983: 996 - 1003\)) reports the accompanying data on amount of milk ingested by each of\(14\)randomly selected infants.

\(\begin{array}{*{20}{l}}{\;\;\;\;\;\;\;\;\;\;\;\;\;\;Infant\;\;\;\;\;\;\;\;\;\;\;\;\;\;\;\;\;\;\;\;\;\;\;\;\;\;\;\;\;\;\;\;\;\;\;\;\;\;\;\;\;\;\;\;\;\;\;\;}\\{\;\;\;\;\;\;\;\;\;\;\;\;\;\;1\;\;\;\;\;\;\;\;\;\;\;\;2\;\;\;\;\;\;\;\;\;\;\;\;3\;\;\;\;\;\;\;\;\;\;\;\;4\;\;\;\;\;\;\;\;\;\;\;\;5}\\{D method\;\;\;\;\;\;\;\;\;\;\;1509\;\;\;\;\;1418\;\;\;\;\;1561\;\;\;\;\;1556\;\;\;\;\;2169}\\{W method\;\;\;\;\;\;\;\;\;\;1498\;\;\;\;\;1254\;\;\;\;\;1336\;\;\;\;\;1565\;\;\;\;\;2000}\\{jifference\;\;\;\;\;\;\;\;\;\;\;\;11\;\;\;\;\;\;\;\;\;\;164\;\;\;\;\;\;\;225\;\;\;\;\;\;\; - 9\;\;\;\;\;\;\;\;\;\;169}\end{array}\)

\(\begin{array}{*{20}{c}}{}&{Infant}&{}&{}&{}&{}\\{}&6&7&8&9&{10}\\{DD method}&{1760}&{1098}&{1198}&{1479}&{1281}\\{TW method}&{1318}&{1410}&{1129}&{1342}&{1124}\\{Difference}&{442}&{ - 312}&{69}&{137}&{157}\end{array}\)

\(\begin{array}{*{20}{c}}{}&{Infant}&{}&{}&{}\\{}&{11}&{12}&{13}&{14}\\{DD method}&{1414}&{1954}&{2174}&{2058}\\{TW method}&{1468}&{1604}&{1722}&{1518}\\{Difference}&{ - 54}&{350}&{452}&{540}\end{array}\)

a. Is it plausible that the population distribution of differences is normal?

b. Does it appear that the true average difference between intake values measured by the two methods is something other than zero? Determine the\(P\)-value of the test, and use it to reach a conclusion at significance level . \(05\).

Short Answer

Expert verified

Reject null hypothesis.

Step by step solution

01

Step 1:

The Infant data is given in the following table:

\(\begin{array}{*{20}{c}}i&{{\rm{ DD method, }}{x_i}}&{{\rm{ TW method, }}{y_i}}&{{\rm{ Difference, }}{d_i} = {x_i} - {y_i}}\\1&{1509}&{1498}&{11}\\2&{1418}&{1254}&{164}\\3&{1561}&{1336}&{225}\\4&{1556}&{1565}&{ - 9}\\5&{2169}&{2000}&{169}\\6&{1760}&{1318}&{442}\\7&{1098}&{1410}&{ - 312}\\8&{1198}&{1129}&{69}\\9&{1479}&{1342}&{137}\\{10}&{1281}&{1124}&{157}\\{11}&{1414}&{1468}&{ - 54}\\{12}&{1954}&{1604}&{350}\\{13}&{2174}&{1722}&{452}\\{14}&{2058}&{1518}&{540}\\{}&{}&{}&{}\end{array}\)

02

 Step 1: Mapping the graph

The normal probability plot indicated that the differences are normally distributed. It is plausible that the population distribution of differences is normal.

03

b)Step 2: Find the test statistic value

Because the experiment performed on the same\(14\)randomly selected infants, the pair\(t\)test should be used.

The Paired\(t\)Test:

When\(D = X - Y\)(difference between observations within a pair),\({\mu _D} = {\mu _1} - {\mu _2}\)

and null hypothesis

\({H_0}:{\mu _D} = {\Delta _0},\)

the test statistic value for testing the hypotheses is

\(t = \frac{{\bar d - {\Delta _0}}}{{{s_D}/\sqrt n }}\)

where \(\bar d\) and\({s_D}\) are the sample mean and the sample standard deviation of differences\({d_i}\), respectively. In order to use this test, assume that the differences \({D_i}\) are from a normal population. Depending on alternative hypothesis, the \(P\) value can be determined as the corresponding area under the \({t_{n - 1}}\)curve.

04

Find the mean and standard deviation

The hypotheses of interest are\({H_o}:{\mu _D} = 0\)versus\({H_a}:{\mu _D} \ne 0\). The value of test statistic can be obtained when the sample mean and the sample standard deviation of the differences is found.

The Sample Mean\(\bar x\)of observations\({x_1},{x_2}, \ldots ,{x_n}\)is given by

\(\bar x = \frac{{{x_1} + {x_2} + \ldots + {x_n}}}{n} = \frac{1}{n}\sum\limits_{i = 1}^n {{x_i}} \)

The sample mean\(\bar d\)for the differences is

\(\bar d = \frac{1}{{14}} \cdot (11 + 164 + \ldots + 540) = 167.2\)

The delta value is

\({\Delta _0} = 0\)

The only missing value to compute the test statistic value is the sample standard deviation of differences\({d_i}\).

The Sample Variance\({s^2}\)is

\({s^2} = \frac{1}{{n - 1}} \cdot {S_{xx}}\)

\({S_{xx}} = \sum {{{\left( {{x_i} - \bar x} \right)}^2}} = \sum {x_i^2} - \frac{1}{n} \cdot {\left( {\sum {{x_i}} } \right)^2}\)

The Sample Standard Deviation\(s\)is

\(s = \sqrt {{s^2}} = \sqrt {\frac{1}{{n - 1}} \cdot {S_{xx}}} \)

The sample variance is

\(\begin{array}{l}s_D^2 = \frac{1}{{14 - 1}} \cdot \left( {{{(11 - 167.2)}^2} + {{(164 - 167.2)}^2} + \ldots + {{(540 - 167.2)}^2}} \right)\\ = 52,080.18\end{array}\)

and the sample standard deviation\({s_D} = \sqrt {52,080.18} = 228\)

05

Find the test statistic value

The test statistic value is

\(t = \frac{{\bar d - {\Delta _0}}}{{{s_D}/\sqrt n }} = \frac{{167.2 - 0}}{{228/\sqrt {14} }} = 2.74\)

The test is two-sided where the alternative hypothesis is\({H_a}:{\mu _D} \ne 0\), therefore the\(P\)value is two times the area under the the\({t_{n - 1}} = {t_{14 - 1}} = \$ \$ {t_1}3\)curve to the right of\(|t|\)value

\(P = 2 \cdot P(T > 2.74) = 2 \cdot 0.009 = 0.018\)

where\(T\)has student distribution with\(13\)degrees of freedom, and the probability as computed using software (you can use table in the appendix of the book). At significance level\(0.05\), because

\(P = 0.018 < 0.05\)

reject null hypothesis

at given significance level. There is enough evidence to conclude that the true average difference between the values of the two methods is different than \(0.\)

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Most popular questions from this chapter

To decide whether two different types of steel have the same true average fracture toughness values, n specimens of each type are tested, yielding the following results:

\(\begin{array}{l}\underline {\begin{array}{*{20}{c}}{ Type }&{ Sample Average }&{ Sample SD }\\1&{60.1}&{1.0}\\2&{59.9}&{1.0}\\{}&{}&{}\end{array}} \\\end{array}\)

Calculate the P-value for the appropriate two-sample \(z\) test, assuming that the data was based on \(n = 100\). Then repeat the calculation for \(n = 400\). Is the small P-value for \(n = 400\) indicative of a difference that has practical significance? Would you have been satisfied with just a report of the P-value? Comment briefly.a

Using the traditional formula, a \(95\% \) CI for \({p_1} - {p_2}\)is to be constructed based on equal sample sizes from the two populations. For what value of \(n( = m)\)will the resulting interval have a width at most of .1, irrespective of the results of the sampling?

Refer back to the previous exercise.

a. By far the most frequently tested null hypothesis when data is paired is\({H_0}:{\mu _D} = 0\). Is that a sensible hypothesis in this context? Explain.

b. Carry out a test of hypotheses to decide whether there is compelling evidence for concluding that on average diagnosis occurs more than\(\;25\)months after the onset of symptoms.

Reliance on solid biomass fuel for cooking and heating exposes many children from developing countries to high levels of indoor air pollution. The article 鈥淒omestic Fuels, Indoor Air Pollution, and Children鈥檚 Health鈥 (Annals of the N.Y. Academy of Sciences, \(2008:209 - 217\)) presented information on various pulmonary characteristics in samples of children whose households in India used either biomass fuel or liquefied petroleum gas (\(LPG\)). For the \(755\) children in biomass households, the sample mean peak expiratory flow (a person鈥檚 maximum speed of expiration) was \(3.30L/s\), and the sample standard deviation was \(1.20\). For the \(750\) children whose households used liquefied petroleum gas, the sample mean \(PEF\) was \(4.25\) and the sample standard deviation was \(1.75\).

a. Calculate a confidence interval at the \(95\% \) confidence level for the population mean \(PEF\) for children in biomass households and then do likewise for children in \(LPG\) households. What is the simultaneous confidence level for the two intervals?

b. Carry out a test of hypotheses at significance level \(.01\) to decide whether true average \(PEF\) is lower for children in biomass households than it is for children in \(LPG\) households (the cited article included a P-value for this test)

c. \(FE{V_1}\), the forced expiratory volume in \(1\) second, is another measure of pulmonary function. The cited article reported that for the biomass households the sample mean FEV1 was \(2.3L/s\) and the sample standard deviation was \(.5L/s\). If this information is used to compute a \(95\% \) \(CI\) for population mean \(FE{V_1}\), would the simultaneous confidence level for this interval and the first interval calculated in (a) be the same as the simultaneous confidence level determined there? Explain

Refer to Exercise\(34.\)Describe the pooled\(t\)test for testing\({H_0}:{\mu _1} - {\mu _2} = {\Delta _0}\)when both population distributions are normal with\({\sigma _1} = {\sigma _2}\). Then use this test procedure to test the hypotheses suggested in Exercise\(33\)

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