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Cerebral Blood Flow Cerebral blood flow (CBF) in the brains of healthy people is normally distributed with a mean of 74 and a standard deviation of 16 a. What proportion of healthy people will have CBF readings between 60 and \(80 ?\) b. What proportion of healthy people will have CBF readings above \(100 ?\) c. If a person has a CBF reading below \(40,\) he is classified as at risk for a stroke. What proportion of healthy people will mistakenly be diagnosed as "at risk"?

Short Answer

Expert verified
Answer: Approximately 45.61% of healthy people have CBF readings between 60 and 80, about 5.22% of healthy people have CBF readings above 100, and about 1.66% of healthy people will be mistakenly diagnosed as "at risk" for a stroke.

Step by step solution

01

Convert CBF readings to z-scores

To convert the CBF readings to z-scores, we can use the formula: \[z = \frac{x - \mu}{\sigma}\] where z is the z-score, x is the CBF reading, μ is the mean, and σ is the standard deviation. For the lower end of the range, 60: \[z_{60} = \frac{60 - 74}{16} = -0.875\] For the upper end of the range, 80: \[z_{80} = \frac{80 - 74}{16} = 0.375\]
02

Calculate the proportion using the standard normal distribution table

Using a standard normal distribution table (or calculator), find the area to the left of the z-scores obtained in step 1. For z = -0.875, the area to the left is 0.1909. For z = 0.375, the area to the left is 0.6470. Then subtract the lower area from the upper area to get the proportion between the two z-scores: \[0.6470 - 0.1909 = 0.4561\] Thus, about 45.61% of healthy people will have CBF readings between 60 and 80. #b. Proportion above 100#
03

Convert the CBF reading to a z-score

Using the same formula as before, For the CBF reading of 100: \[z_{100} = \frac{100 - 74}{16} = 1.625\]
04

Calculate the proportion using the standard normal distribution table

Using a standard normal distribution table (or calculator), find the area to the left of the z-score obtained in step 1. For z = 1.625, the area to the left is 0.9478. Since we are interested in the proportion above 100, we need to consider the area to the right of the z-score. The area to the right can be found by subtracting the area to the left from 1: \[1 - 0.9478 = 0.0522\] Thus, about 5.22% of healthy people will have CBF readings above 100. #c. Proportion of healthy people diagnosed as "at risk"#
05

Convert the CBF reading to a z-score

Using the same formula as before, For the CBF reading of 40: \[z_{40} = \frac{40 - 74}{16} = -2.125\]
06

Calculate the proportion using the standard normal distribution table

Using a standard normal distribution table (or calculator), find the area to the left of the z-score obtained in step 1. For z = -2.125, the area to the left is 0.0166. Thus, about 1.66% of healthy people will be mistakenly diagnosed as "at risk" for a stroke.

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Key Concepts

These are the key concepts you need to understand to accurately answer the question.

Z-score
The Z-score is a statistical measurement that describes how many standard deviations an element is from the mean. This is important when analyzing data that follows a normal distribution, like cerebral blood flow. By converting individual data points into Z-scores, you can easily determine their position relative to the overall data set.
To calculate the Z-score, you use the formula: \(z = \frac{x - \mu}{\sigma}\). Here, \(x\) represents the data point (or "Cerebral Blood Flow" reading in this context), \(\mu\) is the mean of the data set, and \(\sigma\) is the standard deviation.
Using Z-scores, we can find out what percentage of the data falls below, above, or between specific values by using a standard normal distribution table. This is how we analyze different ranges of CBF readings described in the problem.
Standard Deviation
Standard deviation is a measure of how much variation or dispersion exists from the mean in a data set. In simpler terms, it tells us how spread out the numbers are.
For cerebral blood flow, the standard deviation gives us insight into the variability of blood flow readings among healthy individuals. A smaller standard deviation would mean the CBF readings are closer to the mean, while a larger standard deviation indicates a wider spread of readings.
In our problem, the mean CBF is 74 ml/100g/min, and the standard deviation is 16. This means that most healthy individuals will have CBF readings that fall within 16 units of the mean, providing a foundational understanding for calculating Z-scores and ultimately, estimating probabilities.
Cerebral Blood Flow
Cerebral blood flow refers to the blood supply that reaches the brain in a given time period. It is crucial for maintaining normal brain function and is typically measured in ml/100g/min.
In our context, CBF is assumed to be normally distributed, which is a common assumption for biological measurements. This means most individuals will have CBF readings close to the average value of 74, with fewer readings at the extremes.
Understanding the normal distribution of CBF allows us to utilize Z-scores and probability tables to predict the likelihood of certain ranges or thresholds, such as determining the proportion of healthy individuals with readings above 100, or assessing who might be at risk based on CBF levels below 40.
Probability Distribution
Probability distribution, in statistics, is a function that describes how likely it is for different outcomes to occur. In the case of a normal distribution, it helps us understand how CBF readings are spread among the population.
It is characterized by its bell-shaped curve, where most data points cluster around the mean. Here, the mean is 74 and the standard deviation is 16.
  • The area under this curve represents probabilities and is always equal to 1.
  • It helps us calculate probabilities for CBF readings between specific values (like between 60 and 80)
    or above certain thresholds (like above 100).
Therefore, by knowing the characteristics of a normal distribution, we can apply probability concepts to identify patterns and anticipate the likelihood of atypical CBF readings in healthy people.

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