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In a clinical trial of the effectiveness of echinacea for preventing

colds, the results in the table below were obtained (based on data from 鈥淎n Evaluation of Echinacea Angustifoliain Experimental Rhinovirus Infections,鈥 by Turner et al., NewEngland Journal of Medicine,Vol. 353, No. 4). Use a 0.05 significance level to test the claim that getting a cold is independent of the treatment group. What do the results suggest about the

effectiveness of echinacea as a prevention against colds?

Treatment Group


Placebo

Echinacea:

20% Extract

Echinacea:

60% Extract

Got a Cold

88

48

42

Did Not Get a Cold

15

4

10

Short Answer

Expert verified

Getting a cold is independent of the treatment group. Thus, Echinacea is not effective to prevent colds.

Step by step solution

01

Given information

The data forthe effectiveness of Echinacea for preventing colds is provided.

The level of significance is 0.05.

02

Compute the expected frequencies

Assume that random selections are done for subjects, and each subject is assigned randomly to each group.

Theexpected frequency formulais computed as,

\(E = \frac{{\left( {row\;total} \right)\left( {column\;total} \right)}}{{\left( {grand\;total} \right)}}\)

The row and column total for the observed frequencies is represented as,


Placebo

Echinacea:

20% Extract

Echinacea:

60% Extract

Row Total

Got a Cold

88

48

42

178

Did Not Get a Cold

15

4

10

29

Column Total

103

52

52

207

Theexpected frequency tableis represented as,


Placebo

Echinacea:

20% Extract

Echinacea:

60% Extract

Got a Cold

88.5700

44.7150

44.7150

Did Not Get a Cold

14.4300

7.2850

7.2850

Each expected value is greater than 5.

Thus, the requirements for the test are satisfied.

03

State the null and alternate hypothesis

The hypotheses are stated as:

\({H_0}:\)Getting a cold is independent of the treatment group.

\({H_1}:\)Getting a cold is dependent on the treatment group.

04

Compute the test statistic

The value of the test statistic is computed as,

\(\begin{aligned}{c}{\chi ^2} = \sum {\frac{{{{\left( {O - E} \right)}^2}}}{E}} \\ = \frac{{{{\left( {88 - 88.5700} \right)}^2}}}{{88.5700}} + \frac{{{{\left( {48 - 44.7150} \right)}^2}}}{{44.7150}} + ... + \frac{{{{\left( {10 - 7.2850} \right)}^2}}}{{7.2850}}\\ = 2.925\end{aligned}\)

Therefore, the value of the test statistic is 2.925.

05

Compute the degrees of freedom

The degrees of freedomare computed as,

\(\begin{aligned}{c}\left( {r - 1} \right)\left( {c - 1} \right) = \left( {2 - 1} \right)\left( {3 - 1} \right)\\ = 2\end{aligned}\)

Therefore, the degrees of freedom are 2.

06

Compute the critical value

From the chi-square table, the critical value for the row corresponding to 2 degrees of freedom and at 0.05 level of significance 5.991.

Therefore, the critical value is 5.991.

The P-value is obtained as 0.232.

07

State the decision

Since the critical value (5.991) is greater than the value of the test statistic (2.925). In this case, the null hypothesis fails to be rejected.

Therefore, the decision is that null hypothesis is failed to be rejected.

The P-value is obtained as 0.2316.

08

State the conclusion

There issufficient evidence to support the claimthat getting a cold is independent of the treatment group.

Thus, it can be said that Echinacea is not effective to prevent colds.

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Most popular questions from this chapter

In Exercises 5鈥20, conduct the hypothesis test and provide the test statistic and the P-value and, or critical value, and state the conclusion.

Baseball Player Births In his book Outliers, author Malcolm Gladwell argues that more baseball players have birth dates in the months immediately following July 31, because that was the age cutoff date for nonschool baseball leagues. Here is a sample of frequency counts of months of birth dates of American-born Major League Baseball players starting with January: 387, 329, 366, 344, 336, 313, 313, 503, 421, 434, 398, 371. Using a 0.05 significance level, is there sufficient evidence to warrant rejection of the claim that American-born Major League Baseball players are born in different months with the same frequency? Do the sample values appear to support Gladwell鈥檚 claim?

The table below shows results since 2006 of challenged referee calls in the U.S. Open. Use a 0.05 significance level to test the claim that the gender of the tennis player is independent of whether the call is overturned. Do players of either gender appear to be better at challenging calls?

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No

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161

376

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Do World War II Bomb Hits Fit a Poisson Distribution? In analyzing hits by V-1 buzz bombs in World War II, South London was subdivided into regions, each with an area of 0.25\(k{m^2}\). Shown below is a table of actual frequencies of hits and the frequencies expected with the Poisson distribution. (The Poisson distribution is described in Section 5-3.) Use the values listed and a 0.05 significance level to test the claim that the actual frequencies fit a Poisson distribution. Does the result prove that the data conform to the Poisson distribution?

Number of Bomb Hits

0

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2

3

4

Actual Number of Regions

229

211

93

35

8

Expected Number of Regions

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In a study of high school students at least 16 years of age, researchers obtained survey results summarized in the accompanying table (based on data from 鈥淭exting While Driving and Other Risky Motor Vehicle Behaviors Among U.S. High School Students,鈥 by O鈥橫alley, Shults, and Eaton, Pediatrics,Vol. 131, No. 6). Use a 0.05 significance level to

test the claim of independence between texting while driving and driving when drinking alcohol. Are those two risky behaviors independent of each other?


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Yes

No

Texted while driving

731

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No Texting while driving

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Alert nurses at the Veteran鈥檚 Affairs Medical Center in Northampton, Massachusetts, noticed an unusually high number of deaths at times when another nurse, Kristen Gilbert, was working. Those same nurses later noticed missing supplies of the drug epinephrine, which is a synthetic adrenaline that stimulates the heart. Kristen Gilbert was arrested and charged with four counts of murder and two counts of attempted murder. When seeking a grand jury indictment, prosecutors provided a key piece of evidence consisting of the table below. Use a 0.01 significance level to test the defense claim that deaths on shifts are independent of whether Gilbert was working. What does the result suggest about the guilt or innocence of Gilbert?

Shifts With a Death

Shifts Without a Death

Gilbert Was Working

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Gilbert Was Not Working

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