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Magazine Chapter 24: Q8P (page 1111)
Draw the mechanism for the third reaction in glycolysis鈥攖he reaction of fructose-6-phosphate with ATP to form fructose-1,6-bisphosphate.
Short Answer
Step by step solution
Step-by-Step SolutionStep 1: Conversion of fructose-6-phosphate with ATP to form fructose-1, 6-bisphosphate
The conversion of fructose 6-phosphate to fructose 1,6- bisphosphate is one of the phosphoryl transfer reactions. The reaction is irreversible under physiological conditions. This reaction is catalyzed by phosphofructokinase. The rate of the reaction depends on the activity of an enzyme.
Mechanism of the conversion
In the given transformation lone pair of oxygen of fructose 6-phosphate attacks the phosphorus of ATP molecule so that fructose-6-phosphate is converted to fructose-1, 6-bisphosphate.
The mechanism of the reaction is as follows;
Glycolysis (reaction 3)
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