/*! This file is auto-generated */ .wp-block-button__link{color:#fff;background-color:#32373c;border-radius:9999px;box-shadow:none;text-decoration:none;padding:calc(.667em + 2px) calc(1.333em + 2px);font-size:1.125em}.wp-block-file__button{background:#32373c;color:#fff;text-decoration:none} Q1P In acidic solutions, nucleosides... [FREE SOLUTION] | 91影视

91影视

Log out

Learning Materials

Features

Discover

Chapter 26: Q1P (page 1159)

In acidic solutions, nucleosides are hydrolyzed to a sugar and a heterocyclic base. Propose a mechanism for this reaction.

Short Answer

Expert verified

A compound containing a base bonded to d-ribose or to 2鈥�-deoxy-d-ribose is called a nucleoside or these are glycosylamines made by attaching a nucleobase to a ribose or deoxyribose ring.

Adenosine

Guanosine

Deoxyadenosine

Deoxyguanosine

Step by step solution

01

Step 1:Nucleoside

A compound containing a base bonded to d-ribose or to 2鈥�-deoxy-d-ribose is called a nucleoside or these are glycosylamines made by attaching a nucleobase to a ribose or deoxyribose ring.

Adenosine

Guanosine

Deoxyadenosine

Deoxyguanosine

02

Mechanism for the reaction

Nucleoside undergoes hydrolysis to form sugar and base. The example is represented as follows:

Hydrolysis of nucleoside

The mechanism for the reaction is as:

Mechanism

Unlock Step-by-Step Solutions & Ace Your Exams!

  • Full Textbook Solutions

    Get detailed explanations and key concepts

  • Unlimited Al creation

    Al flashcards, explanations, exams and more...

  • Ads-free access

    To over 500 millions flashcards

  • Money-back guarantee

    We refund you if you fail your exam.

Over 30 million students worldwide already upgrade their learning with 91影视!

One App. One Place for Learning.

All the tools & learning materials you need for study success - in one app.

Get started for free

Most popular questions from this chapter

Using the D, A, and D/A designations in Problem 3, indicate how base pairing would be affected if the bases existed in the enol form

RNAase, the enzyme that catalyzes the hydrolysis of RNA, has two catalytically active histidine residues at its active site. One of the histidine residues is catalytically active in its acidic form, and the other is catalytically active in its basic form. Propose a mechanism for RNAase.

Human immunodeficiency virus (HIV) is the retrovirus that causes AIDS. AZT was one of the first drugs designed to interfere with retroviral DNA synthesis. When cells take up AZT, they convert it to AZT-triphosphate. Explain how AZT interferes with DNA synthesis.

Indicate whether each functional group of the five heterocyclic bases in nucleic acids is a hydrogen bond acceptor (A), a hydrogen bond donor (D), or both (D/A).

The amino acid sequences of peptide fragments obtained from a normal protein were compared with those obtained from the same protein synthesized by a defective gene. They were found to differ in only one peptide fragment. Their amino acid sequences are shown here:

Normal: Gln-Tyr-Gly-Thr-Arg-Tyr-Val

Mutant: Gln-Ser-Glu-Pro-Gly-Thr

a. What is the defect in DNA?

b. It was later determined that the normal peptide fragment is an octapeptide with a C-terminal Val-Leu. What is the C-terminal amino acid of the mutant peptide?
See all solutions

Recommended explanations on Chemistry Textbooks

Chemical Analysis

Read Explanation

Making Measurements

Read Explanation

Inorganic Chemistry

Read Explanation

Organic Chemistry

Read Explanation

Ionic and Molecular Compounds

Read Explanation

Nuclear Chemistry

Read Explanation
View all explanations

What do you think about this solution?

We value your feedback to improve our textbook solutions.

Study anywhere. Anytime. Across all devices.