Chapter 9: Q20P (page 411)
Draw the configuration(s) of the substitution product(s) formed from the reaction of the following compounds with the indicated nucleophiles:

Short Answer
a)

It follows SN2 mechanism.
b.


It follows SN2 mechanism.
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Chapter 9: Q20P (page 411)
Draw the configuration(s) of the substitution product(s) formed from the reaction of the following compounds with the indicated nucleophiles:

a)

It follows SN2 mechanism.
b.


It follows SN2 mechanism.
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Starting with cyclohexene, how could the following compounds be prepared?
a. methoxycyclohexane
b. cyclohexylmethylamine
c. dicyclohexyl ether
Question:What product is formed when 1-bromopropane reacts with each of the following nucleophiles?
a. HO-
b. -NH2
c. CH3S-
d. HS-
e. CH3O-
f. CH3NH2
a. Explain why the reaction of an alkyl halide with ammonia gives a low yield of primary amine.
b. Explain why a much better yield of primary amine is obtained from the reaction of an alkyl halide with an azide ion (-N3), followed by catalytic hydrogenation. (Hint: An alkyl azide is not nucleophilic.)

a. Explain why 1-bromo-2,2-dimethylpropane has difficulty undergoing both SN2 and SN1 reactions.
b. Can it undergo E2 and E1 reactions?
Draw the substitution product formed by each of the following SN2 reactions:
a. trans-1-iodo-4-ethylcyclohexane and methoxide ion
b. cis-1-chloro-3-methylcyclobutane and ethoxide ion
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