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Chapter 22: Q5Pb (page 1155)

Predict the major products of the following reactions.

b)

Short Answer

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b)

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01

Alkylation of enolate ions

Lithium diisopropyl amide (LDA) is used for the alkylation of enolate ions as it is a strong base and transforms the ketone to an enolate.

02

Predicting the major products of the reaction

(b) The reaction of the given compound with LDA and CH3CH2Br is 2-ethyloctahydronaphthalen-1(2H)-one. The reaction is given below:

Product of reaction (b)

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