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Chapter 8: Problem 13

With regard to the segregation of centromeres, why is adjacent- 2 segregation less frequent than alternate or adjacent-1 segregation?

Short Answer

Expert verified
Adjacent-2 segregation is less frequent because it leads to severely unbalanced gametes, most of which will not be viable due to the huge imbalances of genes and chromosomes. It is also prevented by correct spindle attachment during anaphase I of meiosis.

Step by step solution

01

Understanding chromosome segregation during meiosis

In meiosis, chromosomes segregate so that each daughter cell receives one chromosome from each homologous pair. This ensures genetic diversity.
02

Understanding alternate segregation

Alternate segregation happens when homologous centromeres move to opposite poles during anaphase I of meiosis. This results in balanced gametes with no duplicate or missing genetic information, and it's the most common type of segregation.
03

Understanding adjacent-1 segregation

Adjacent-1 segregation occurs when homologous centromeres move to the same pole during anaphase I. This results in gametes with duplications and deletions of certain genes, but the overall number of chromosomes is still balanced.
04

Understanding adjacent-2 segregation

Adjacent-2 segregation is when sister centromeres, instead of homologous centromeres, move to the same pole during anaphase I. This results in gametes with imbalances of both genes and chromosomes, carrying both homologous chromosomes and both sister chromatids of one homolog.
05

Understanding why adjacent-2 segregation is less frequent

Adjacent-2 segregation is less frequent because it results in severely unbalanced gametes. Most of these will not be viable due to the large-scale imbalances of genes and chromosomes, therefore reducing the frequency of adjacent-2 segregation. It鈥檚 also less common because correct spindle attachment usually prevents the simultaneous movement of sister centromeres to the same pole during anaphase I.

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Most popular questions from this chapter

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