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Explain why 尾 sheets are less likely to form than 伪 helices during the earliest stages of protein folding.

Short Answer

Expert verified

The hydrogen bonds in sheets require less energy to stabilise because they are weaker than those in sheets.

Step by step solution

01

Definition of protein folding

Protein folding is the process by which a polypeptide chain folds in its natural 3D form to become a physiologically active protein.

02

Step 2: Formation of β sheets is less likely than α helices

In a sheet, two peptide bonds are required to produce one hydrogen bond, but in a helix, the hydrogen bond is formed once the three residues are fixed. Hence, formation of sheets is less likely than helices.

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