Chapter 3: Q23P. (page 78)
Some RNA molecules are covalently modified by methylation at the N鈦秔osition in adenosine residues. Draw the structure of the modified nucleoside.
Short Answer
The methylated structure of adenine is N鈦-methyladenosine.

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Chapter 3: Q23P. (page 78)
Some RNA molecules are covalently modified by methylation at the N鈦秔osition in adenosine residues. Draw the structure of the modified nucleoside.
The methylated structure of adenine is N鈦-methyladenosine.

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A diploid organism with a 45,000-kb haploid genome contains 21% G residues. Calculate the number of A, C, G, and T residues in the DNA of each cell in this organism.
Name the following nucleotide.

Use your answer to Problem 27 to determine the relative pK values of N鈧 in cytosine and in uracil
In many organisms, DNA is modified by methylation. Draw the structure of 5-methylcytosine, a base that occurs with high frequency in inactive DNA.
Refer to the diagram of pUC18 (Fig. 3-24) to determine which restriction enzymes you could use to insert a gene that would interfere with production of 尾-galactosidase by the host cell.
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