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Chapter 23: Q7CP (page 812)

How are CTP and UTP derived from UMP?

Short Answer

Expert verified

The synthesis of CTP from UTP is as follows:

UTP+Glutamine+ATP+H2O鈫�CTPsynthaseCTP+Glutamate+ADP+Pi

The synthesis of UTP from UMP is as follows:

Step by step solution

01

Pyrimidines

Pyrimidines are a type of nitrogenous bases used to form deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). The bases included in this category are uracil, thymine, and cytosine.

02

Synthesis of UTP from UMP

The nucleotide uridine triphosphate is synthesized from uridine monophosphate in two enzymatic steps. These steps are as follows:

03

Synthesis of CTP from UTP

The synthesis of cytidine triphosphate (CTP) occurs from UTP in one enzymatic step, which is:

UTP+Glutamine+ATP+H2O鈫�CTPsynthaseCTP+Glutamate+ADP+Pi

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Most popular questions from this chapter

What is the function of the purine nucleotide cycle?

List the starting materials and cofactors required for IMP biosynthesis.

Rats are given cytidine that is14C-labeled at both its base and ribose components. Their DNA is then extracted and degraded with nucleases. Describe the labeling pattern of the recovered deoxycytidylate residues if deoxycytidylate production in the cell followed a pathway in which (a) intact CDP is reduced to dCDP, and (b) CDP is broken down to cytosine and ribose before reduction.

Why is gout more prevalent in populations that eat relatively large amounts of meat?

From which purine is caffeine-derived?
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