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Chapter 24: Q6CP (page 847)

Why is it necessary for naturally occurring DNA molecules to be negatively supercoiled?

Short Answer

Expert verified

The negative supercoiling prepares the molecule for the molecules that need separation of the DNA strands.

Step by step solution

01

DNA

DNA constitutes a group of molecules that is responsible for transferring genetic materials from the parents to the offspring. This is correct for viruses as several of the entities contain DNA or RNA as the genetic material.

02

The reason why the naturally occurring DNA molecules are negatively supercoiled

Negative supercoiling is the left handed coiling of DNA that makes the winding occur in the anticlockwise direction. It is necessary that the naturally occurring DNA molecules are negatively supercoiled as the negative supercoiling prepares the molecule for the molecules that need separation of the DNA strands.

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Most popular questions from this chapter

The asterisk in the structure shown in Problem 31 indicates the site where the base is attached via a two-carbon linker. Compare the overall backbone length for a PNA and a DNA molecule and explain why the two molecules can form base-paired duplexes.

Which of the DNAs shown in Figure 24-8 would move fastest during agarose gel electrophoresis?

Why does it make metabolic sense for UTP to inhibit carbamoylphosphate synthetase II, whereas ATP activates the enzyme?

The melting curve for the polyribonucleotide poly(A) is shown below.

(a) Explain why absorbance increases with increasing temperature.

(b) Why does the shape of the curve differ from the one shown in Fig. 24-22?

How is the melting curve of duplex DNA affected by decreasing the ionic strength of the solution?
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