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Describe the levels of DNA packaging in eukaryotic cells, from B-DNA to a metaphase chromosome

Short Answer

Expert verified

The three chromatin levels are:

1. DNA wrapping 鈥渂eads on the string鈥.

2. 30 nm chromatin fiber with compact nucleosomes

3. DNA packaging into mitotic chromosomes

Step by step solution

01

DNA packaging

DNA packaging constitutes the folding of an organism鈥檚 DNA into a compact structure that fits inside the nucleus of the cell. The proteins responsible for DNA packaging are histones.

02

The levels of DNA packaging in eukaryotic cells, from B_DNA to a metaphase chromosome

B-DNA of eukaryotic chromatin winds around the histone octamers to generate a nucleosome, which is further condensed by linker histones. The additional condensation happens when chromatin folds into 30 nm diameter filaments, which are then connected in loops to a fibrous protein scaffold to finally create a condensed metaphase chromosome.

The three chromatin levels are:

1. DNA wrapping 鈥渂eads on the string鈥.

2. 30 nm chromatin fiber with compact nucleosomes

3. DNA packaging into mitotic chromosomes

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