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Chapter 25: Q10CP (page 897)

Describe the four-factor that contribute to the high fidelity of DNA replication?

Short Answer

Expert verified

DNA replication is a process by which one original DNA molecule produces two identical copies.

Step by step solution

01

DNA Replication is highly specific

It is also called asemi-conservative process, which is the process by whichDNA is doubled.A new DNA is made by an enzyme termed DNA polymerase.

These DNA polymerases also play important role in the fidelity of DNA replication.

02

Factors that contribute to the high fidelity of DNA replication

There are many factors that responsible for high fidelity of replication

(i) DNA polymerase nucleotide selectivity and proofreading.

(ii) Mismatch repair.

(iii) Balanced supply of nucleotide.

(iv) Condition of DNA template.

Thus, DNA replication has high fidelity.

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Most popular questions from this chapter

The E. coli genome contains 1009 Chi sequences. Do these sequences occur at random, and, if not, how much more or less frequently than random do they occur?

What did Meselson and Stahl's experiment reveal about DNA replication?

Approximately how many Okazaki fragments are synthesized in the replication of the E. colichromosome?

Explain why mutations are more likely to occur on the lagging strand than on the leading strand in eukaryotes

A certain mutant DNA polymerase is error-prone, tending to incorporate C opposite a template A. When such a DNA polymerase replicates a segment of DNA containing an A 路 T base pair, what will be the DNA composition in the daughter cells after (a) one and (b) two rounds of cell division? Assume that DNA repair does not occur.

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