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Chapter 17: Q17-6TYU (page 362)

Using Figure 17.6, identify a 5鈥欌�� 3鈥� sequence of nucleotides in the DNA template strand for an mRNA coding for the polypeptide sequence Phe-Pro-Lys.

(A) 5鈥�-UUUCCCAAA-3鈥�

(B) 5鈥�-GAACCCCTT-3鈥�

(C) 5鈥�-CTTCGGGAA-3鈥�

(D) 5鈥�-AAACCCUUU-3鈥�

Short Answer

Expert verified

  1. The option 鈥�5鈥�-UUUCCCAAA-3鈥欌�� isfalse.

  2. The option 鈥�5鈥�-GAACCCCTT-3鈥欌�� isfalse.

  3. The option 鈥�5鈥�-CTTCGGGAA-3鈥欌�� is true.

  4. The option 鈥�5鈥�-AAACCCUUU-3鈥欌�� is false.

Step by step solution

01

Nitrogenous bases

The nitrogenous bases are adenine, guanine, cytosine, and thymine, which are present in the DNA, while the RNA contains the same except for uracil in place of thymine. They are arranged in a particular sequence and code for amino acids.

02

Explanation of option ‘(A)’

The amino acids are arranged in a particular sequence, and the codons code for them. The DNA template strand cannot contain uracil while the given sequence has uracil, and thus DNA template strand cannot be encoded by this sequence.

Thus, uracil is not a part of the DNA template strand.

Therefore, the given statement is false.

03

Explanation of option ‘(B)’

According to figure 17.6, the given template strand is not the complementary strand of the Phe-Pro-Lys sequence as the sequences are written like the mRNA strand.

Thus, the given sequence is not complementary to the Phe-Pro-Lys sequence.

Therefore, the given statement is false.

04

Explanation of option ‘(C)’

The given sequence5鈥�-CTTCGGGAA-3鈥� is the correct answer because GAA-CGG-CTT codes for Phe-Pro-Lys. The sequence GAA-CGG-CTT will be arranged in reverse order as the DNA template strand is always in reverse.

Thus, the given sequence is the DNA template strand as it is complementary and arranged in reverse order.

Therefore, the given statement is true.

05

Explanation of option ‘(D)’

DNA template strand for an mRNA will contain thymine instead of uracil. The given sequence cannot be a DNA template strand as the adenine of mRNA will be complementary to thymine in DNA and not uracil.

Thus, uracil is absent in DNA.

Therefore, the given statement is false.

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Most popular questions from this chapter

In a research article about Alkaptonuria published in 1902, Garrod suggested that humans inherit two "characters" (alleles) for a particular enzyme and that both parents must contribute a faulty version for the offspring to have Alkaptonuria. Today, would this disorder be called dominant or recessive?

What polypeptide product would you expect from a poly-G mRNA that is 30 nucleotides long?

Evolution accounts for the unity and diversity of life, and the continuity of life is based on heritable information in the form of DNA. In a short essay (100-150words), discuss how the fidelity with which DNA is inherited is related to the processes of evolution. (Review the discussion of proofreading and DNA repair in Concept 16.2)

In the actual experiment, the researchers used 149 sequences to build their sequence logo, which is shown below. There is a stack at each position, even if short, because the sequence logo includes more data. (a) Which three positions in this sequence logo have the most predictable bases? Name the most frequent base at each. (b) Which four positions have the least predictable bases? How can you tell?

Knowing that the genetic code is almost universal, a scientist uses molecular biological methods to insert the human 尾-globin gene(shown in Figure17.12) into bacterial cells, hoping the cell will express it and synthesize functional 尾-globin protein. Instead, the protein produced is non-functional and contains fewer amino acids than does 尾-globin made by a eukaryotic cell. Explain why.
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