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HIV and confirmation testing Refer to Exercise 85. Many of the positive results from EIA tests are false positives. It is therefore common practice to perform a second EIA test on another blood sample from a person whose initial specimen tests positive. Assume that the false positive and false negative rates remain the same for a person’s second test. Find the probability that a person who gets a positive result on both EIA tests has HIV antibodies.

Short Answer

Expert verified

Probability that a person gets positive result on both EIA tests has HIV antibodies is approx.0.3931.

Step by step solution

01

Step 1:Given information

Probability for Antibodies present,

P(A)=1%=0.01

Probability for Antibodies present Positive ElA test,

P(P∣A)=0.9985

Probability for Antibodies present Negative EIA test,

PPc∣A=0.0015

Probability for Antibodies absent Positive EIA test,

PP∣Ac=0.0060

Probability for Antibodies absent Negative ElA test,

PPc∣Ac=0.9940

02

Step 2:Calculation

Let

B: Positive result on both EIA tests

P: Positive result on one ElA test

A: Antibodies present

From the previous problem,

We have

Probability for positive EIA test,

P(P)=0.015925

And

Probability for Positive ElA test and Antibodies present,

P(PandA)=P(A)×P(P∣A)=0.01×0.9985=0.009985

Now,

Apply multiplication rule for independent events, to get theprobability for positive result on both EIA tests,

P(B)=P(P)×P(P)

=0.009985×0.009985

=0.000253605625

Also,

Apply multiplication rule for independent events, to get the probability for antibodies present and positive result on both ElA tests,

P(AandB)=P(AandP)×P(AandP)

=0.009985×0.009985

=0.00009970225

Using conditional probability definition:

P(A∣B)=P(AandB)P(B)=0.0000997002250.000253605625≈0.3931

Thus,

The conditional probability for a person getting positive result on both EIA tests has HIV antibodies is approx.0.3931.

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