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(a) Find the relevant sample proportions in each group and the pooled proportion. (b) Complete the hypothesis test using the normal distribution and show all details. Test whether patients getting Treatment \(\mathrm{A}\) are more likely to survive, if 63 out of 82 getting Treatment A survive and 31 out of 67 getting Treatment B survive.

Short Answer

Expert verified
Using obtained sample and pooled proportions perform hypothesis test. If resulting p-value is less than significance level (typically 0.05), then, we reject the null hypothesis, i.e it is likely that patients getting Treatment A are more likely to survive than those getting Treatment B.

Step by step solution

01

Calculate the Relevant Sample Proportions

We have two treatments given, A and B. The proportion of patients surviving for Treatment A is calculated as the number of success cases divided by the sample size. Thus, \( p_A = 63 / 82 \). Likewise, the proportion of patients surviving for Treatment B can be calculated as \( p_B = 31 / 67 \).
02

Calculate the Pooled Proportion

The pooled proportion is found by adding the number of successful cases for both groups and dividing by the combined sample size. Therefore, \( p_{pooled} = (63 + 31) / (82 + 67) \).
03

Perform the Hypothesis Test

The null hypothesis \( H_0 \) is that success rates for treatments A and B are equal. The alternative hypothesis \( H_A \) is that treatment A has a higher success rate than treatment B. In other words, \( H_0: p_A = p_B \) and \( H_A: p_A > p_B \). The z-score can be calculated using the formula \( z = (p_A - p_B) / \sqrt{ p_{pooled} * (1 - p_{pooled}) * [(1 / n_A) + (1 / n_B)] } \) where \( n_A \) and \( n_B \) are the sample sizes for treatments A and B respectively. Once the z-score is calculated, the p-value can be found from standard normal tables.

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Key Concepts

These are the key concepts you need to understand to accurately answer the question.

Sample Proportions
In hypothesis testing, sample proportions help us understand the characteristics of part of a population. Imagine you are conducting a study on medical treatments, as in the exercise. You are looking at two groups: patients receiving Treatment A and those receiving Treatment B. To know how effective these treatments are, we calculate the sample proportions. For Treatment A, the sample proportion refers to the proportion of patients who survived out of the total number receiving Treatment A. It's calculated as \( p_A = \frac{63}{82} \). This gives us a proportion that represents the success rate of Treatment A. Similarly, for Treatment B, the sample proportion \( p_B \) is calculated as \( p_B = \frac{31}{67} \). This shows the success rate of Treatment B. These proportions provide an initial idea about the effectiveness of each treatment before we dive into further analysis.
Pooled Proportion
The pooled proportion is a crucial concept in hypothesis testing, especially when comparing two proportions, like in the given problem. It provides a way to combine the data from two groups to get a single representation of the overall success across both groups.To calculate the pooled proportion, we add up the number of successes from both groups and divide by the total number of observations in both groups combined. So, for treatments A and B:
  • Number of successes for A is 63 and for B is 31.
  • The total patients sampled in both groups are 82 and 67, respectively.
The pooled proportion \( p_{pooled} \) is calculated as \( p_{pooled} = \frac{63 + 31}{82 + 67} \).The pooled proportion serves as a baseline to compare individual proportions like \( p_A \) and \( p_B \) against. It plays a significant role in calculating the variability and standard error needed for subsequent testing, allowing us to perform accurate comparisons between treatments.
Normal Distribution
In statistical tests, particularly hypothesis testing, the normal distribution is often used to decide if observed deviations from expectations are significant. Think of the classic bell curve – that’s what a normal distribution looks like.In our example, after calculating proportions and the pooled proportion, we perform a hypothesis test using the normal distribution. We start by setting up hypotheses:
  • The null hypothesis \( H_0 \) assumes no difference, meaning \( p_A = p_B \).
  • The alternative hypothesis \( H_A \) suggests Treatment A has a higher survival rate, \( p_A > p_B \).
We then calculate a z-score, which tells us how far and in what direction our sample proportion \( p_A - p_B \) lies from \( 0 \) assuming \( H_0 \) is true. The formula used is \[z = \frac{p_A - p_B}{\sqrt{ p_{pooled} \times (1 - p_{pooled}) \times \left(\frac{1}{n_A} + \frac{1}{n_B}\right) }}\]where \( n_A \) and \( n_B \) are the sample sizes. By comparing the z-score to a standard normal distribution, we find a p-value that helps us decide whether the difference in proportions is statistically significant or not. If the p-value is low, we reject the null hypothesis, supporting that Treatment A is indeed more effective.

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Most popular questions from this chapter

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